# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | JH-VIII-157-02 | 21a | EC50 | = | 245 | nM | ALA3748840 | 6.61 | nM | Homo sapiens | ||
2. | ALA3746678 | 32 | EC50 | = | 161 | nM | ALA3748840 | 6.79 | nM | Homo sapiens | ||
3. | ALA3746522 | 31 | EC50 | = | 252 | nM | ALA3748840 | 6.60 | nM | Homo sapiens | ||
4. | Crizotinib | 14, PF-2341066 | EC50 | = | 370 | nM | ALA3748840 | 6.43 | nM | Homo sapiens | ||
5. | AP26113 | AP26113 | EC50 | = | 1988 | nM | ALA3748840 | 5.70 | nM | Homo sapiens | ||
6. | LDK378 | 6, LDK378 | EC50 | = | 303 | nM | ALA3748840 | 6.52 | nM | Homo sapiens | ||
7. | CH5424802 | 18a, CH5424802 | EC50 | = | 872 | nM | ALA3748840 | 6.06 | nM | Homo sapiens | ||
8. | ALA3746269 | 6q | Activity | 0 | ALA3748157 | Dose-dependent effect | Homo sapiens | |||||
9. | ALA3747774 | 6p | Activity | 0 | ALA3748157 | Dose-dependent effect | Homo sapiens | |||||
10. | ALA3745757 | 6o | Activity | 0 | ALA3748157 | Dose-dependent effect | Homo sapiens | |||||
11. | ALA3746815 | 6n | Activity | 0 | ALA3748157 | Dose-dependent effect | Homo sapiens | |||||
12. | ALA3746565 | 6m | Activity | 0 | ALA3748157 | Dose-dependent effect | Homo sapiens | |||||
13. | ALA3746269 | 6q | Activity | 0 | ALA3748166 | Toxic | Homo sapiens | |||||
14. | ALA3747774 | 6p | Activity | 0 | ALA3748166 | Non-toxic | Homo sapiens | |||||
15. | ALA3745757 | 6o | Activity | 0 | ALA3748166 | Non-toxic | Homo sapiens | |||||
16. | ALA3746815 | 6n | Activity | 0 | ALA3748166 | Toxic | Homo sapiens | |||||
17. | ALA3746565 | 6m | Activity | 0 | ALA3748166 | Non-toxic | Homo sapiens | |||||
18. | ALA3746269 | 6q | Activity | 0 | ALA3748165 | Toxic | Homo sapiens | |||||
19. | ALA3747774 | 6p | Activity | 0 | ALA3748165 | Non-toxic | Homo sapiens | |||||
20. | ALA3745757 | 6o | Activity | 0 | ALA3748165 | Non-toxic | Homo sapiens |