| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  Osimertinib (AZD9291) | 8 | IC50 | = | 0.015 | uM | ALA5127880 | 7.82 | nM | |||
| 2. | Osimertinib (AZD9291) | 8 | IC50 | = | 0.015 | uM | ALA5127879 | 7.82 | nM | |||
| 3. |  1,3,5-Triazine-2,4-diamine, 1-(3-chlorophenyl)-1,6-dihydro-6,6-dimethyl- | 23 | Safety ratio | = | 17.1 | ALA838937 | ||||||
| 4. | 1,3,5-Triazine-2,4-diamine, 1-(3-chlorophenyl)-1,6-dihydro-6,6-dimethyl- | 23 | Safety ratio | = | 178 | ALA841243 | ||||||
| 5. | 1,3,5-Triazine-2,4-diamine, 1-(3-chlorophenyl)-1,6-dihydro-6,6-dimethyl- | 23 | IC50 | = | 8.9 | uM | ALA651284 | 5.05 | nM | |||
| 6. |  ALA161034 | 34 (C121) | Safety ratio | = | 1.8 | ALA838937 | ||||||
| 7. | ALA161034 | 34 (C121) | Safety ratio | = | 71.7 | ALA841243 | ||||||
| 8. | ALA161034 | 34 (C121) | IC50 | = | 8.6 | uM | ALA651284 | 5.07 | nM | |||
| 9. |  ALA22693 | 34 | Safety ratio | = | 92.6 | ALA838937 | ||||||
| 10. | ALA22693 | 34 | Safety ratio | = | 1191 | ALA841243 | ||||||
| 11. | ALA22693 | 34 | IC50 | = | 250 | uM | ALA651284 | nM | ||||
| 12. |  ALA348151 | 46 (C299) | Safety ratio | = | 1.9 | ALA838937 | ||||||
| 13. | ALA348151 | 46 (C299) | Safety ratio | = | 2 | ALA841243 | ||||||
| 14. | ALA348151 | 46 (C299) | IC50 | = | 6.4 | uM | ALA651284 | 5.19 | nM | |||
| 15. |  Pyrimethamine | Pyrimethamine | Safety ratio | = | 1 | ALA838937 | ||||||
| 16. | Pyrimethamine | Pyrimethamine | Safety ratio | = | 500 | ALA841243 | ||||||
| 17. | Pyrimethamine | Pyrimethamine | IC50 | = | 40 | uM | ALA651284 | 4.40 | nM | |||
| 18. |  ALA346963 | 42 (C372) | Safety ratio | = | 12.9 | ALA838937 | ||||||
| 19. | ALA346963 | 42 (C372) | Safety ratio | = | 45 | ALA841243 | ||||||
| 20. | ALA346963 | 42 (C372) | IC50 | = | 1.8 | uM | ALA651284 | 5.75 | nM |
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