# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5179576 | TDB | IC50 | = | 96.56 | uM | ALA5246092 | 4.01 | nM | Homo sapiens | ||
2. | ALA5288373 | 30 | IC50 | = | 197.74 | uM | ALA5246092 | nM | Homo sapiens | |||
3. | ALA5279922 | 3'-O-succinyl-apoptolidin A | IC50 | = | 82 | nM | ALA5231562 | 7.09 | nM | Homo sapiens | ||
4. | ALA5288055 | 2'-O-succinyl-apoptolidin A | IC50 | = | 91 | nM | ALA5231562 | 7.04 | nM | Homo sapiens | ||
5. | ALA5277369 | Apoptolidin C | IC50 | = | 24 | uM | ALA5231559 | 4.62 | nM | Homo sapiens | ||
6. | ALA5272182 | Apoptolidin B | IC50 | = | 7 | uM | ALA5231559 | 5.16 | nM | Homo sapiens | ||
7. | Apoptolidin | Apoptolidin A | IC50 | = | 32 | uM | ALA5231559 | 4.50 | nM | Homo sapiens | ||
8. | ALA5266745 | Apoptolidin G | IC50 | = | 150 | uM | ALA5231559 | nM | Homo sapiens | |||
9. | ALA5277987 | Apoptolidin F | IC50 | > | 1000 | uM | ALA5231559 | nM | Homo sapiens | |||
10. | ALA5268068 | Apoptolidin E | IC50 | < | 100 | uM | ALA5231559 | nM | Homo sapiens | |||
11. | ALA5288536 | Apoptolidin D | IC50 | = | 110 | uM | ALA5231559 | nM | Homo sapiens | |||
12. | ALA5196874 | (-)-53; MU1656 | Activity | 0 | ALA5162019 | NA | Homo sapiens | |||||
13. | ALA5188654 | 197 | IC50 | = | 3.56 | nM | ALA5126807 | 8.45 | nM | Homo sapiens | ||
14. | EGFR inhibitor 57 | 57 | GI50 | = | 0.35 | uM | ALA5120446 | nM | Homo sapiens | |||
15. | Osimertinib (AZD9291) | 8 | IC50 | = | 1.084 | uM | ALA4378488 | 5.96 | nM | Homo sapiens | ||
16. | ALA4592472 | 4j | IC50 | = | 6.42 | uM | ALA4378488 | 5.19 | nM | Homo sapiens | ||
17. | ALA4441606 | (+)-4i | IC50 | = | 1.34 | uM | ALA4378488 | 5.87 | nM | Homo sapiens | ||
18. | ALA4441606 | (+)-4i | IC50 | = | 1.087 | uM | ALA4378488 | 5.96 | nM | Homo sapiens | ||
19. | ALA4441606 | (+)-4i | IC50 | = | 1.048 | uM | ALA4378488 | 5.98 | nM | Homo sapiens | ||
20. | ALA4570333 | 4h | IC50 | = | 1.045 | uM | ALA4378488 | 5.98 | nM | Homo sapiens |