# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA261592 | 13, BMS-645737 | MED | = | 7.5 | mg kg-1 | ALA929448 | mg kg-1 | Homo sapiens | |||
2. | ALA261592 | 13, BMS-645737 | Activity | >= | 50 | % | ALA925774 | % | Homo sapiens | |||
3. | ALA261592 | 13, BMS-645737 | Activity | >= | 50 | % | ALA925773 | % | Homo sapiens | |||
4. | ALA261592 | 13, BMS-645737 | Activity | 0 | ALA929448 | Dose-dependent effect | Homo sapiens | |||||
5. | ALA261592 | 13, BMS-645737 | IC50 | > | 2500 | nM | ALA929444 | nM | Homo sapiens | |||
6. | ALA408444 | 8, brivanib alaninate, BMS-582664 | TGI | = | 97 | % | ALA935259 | % | Homo sapiens | |||
7. | ALA408444 | 8, brivanib alaninate, BMS-582664 | TGI | = | 85 | % | ALA935258 | % | Homo sapiens | |||
8. | ALA408444 | 8, brivanib alaninate, BMS-582664 | Activity | 0 | ALA935257 | Dose-dependent effect | Homo sapiens | |||||
9. | ALA258046 | 37 | Inhibition | = | 66 | % | ALA950147 | % | Homo sapiens | |||
10. | ALA258046 | 37 | Inhibition | = | 0 | % | ALA950146 | % | Homo sapiens | |||
11. | ALA405495 | 4 | IC50 | = | 0.4 | uM | ALA926199 | 6.40 | nM | Homo sapiens | ||
12. | ALA2367923 | 5 | IC50 | = | 2.3 | uM | ALA926199 | 5.64 | nM | Homo sapiens | ||
13. | ALA386131 | 2 | IC50 | = | 0.2 | uM | ALA926199 | 6.70 | nM | Homo sapiens | ||
14. | ALA405495 | 4 | IC50 | = | 10.1 | uM | ALA926198 | 5.00 | nM | Homo sapiens | ||
15. | ALA2367923 | 5 | IC50 | = | 130 | uM | ALA926198 | nM | Homo sapiens | |||
16. | ALA386131 | 2 | IC50 | = | 6.2 | uM | ALA926198 | 5.21 | nM | Homo sapiens | ||
17. | ALA398439 | 17a | IC50 | = | 0.2 | uM | ALA926199 | 6.70 | nM | Homo sapiens | ||
18. | ALA398439 | 17a | IC50 | = | 5.7 | uM | ALA926198 | 5.24 | nM | Homo sapiens | ||
19. | Paclitaxel | Paclitaxel | IC50 | = | 0.2 | uM | ALA926198 | 6.70 | nM | Homo sapiens | ||
20. | AC480 (BMS-599626) | 13, BMS-599626 | TGI | = | 99 | % | ALA1054506 | % | Homo sapiens |