| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  OTS964 | BDBM149202 | TGI | = | 113 | % | ALA4261715 | % | Homo sapiens | |||
| 2. | OTS964 | BDBM149202 | TGI | = | 110 | % | ALA4261714 | % | Homo sapiens | |||
| 3. | OTS964 | BDBM149202 | IC50 | = | 7.6 | nM | ALA4261699 | 8.12 | nM | Homo sapiens | ||
| 4. |  OTS514 | BDBM149124 | IC50 | = | 1.5 | nM | ALA4261699 | 8.82 | nM | Homo sapiens | ||
| 5. | OTS514 | BDBM149124 | TGI | = | 104 | % | ALA4261713 | % | Homo sapiens | |||
| 6. |  (2R,4aR)-11-Chloro-9-fluoro-10-(2-fluoro-6-hydroxyphenyl)-2,6-dimethyl-3-(prop-2-enoyl)-2,3,4,4a-tetrahydro-1H-pyrazino[1′,2′:4,5]pyrazino[2,3-c]quinolin-5(6H)-one | 25 | GI | 0 | ALA4404202 | Not Active | Homo sapiens | |||||
| 7. | (2R,4aR)-11-Chloro-9-fluoro-10-(2-fluoro-6-hydroxyphenyl)-2,6-dimethyl-3-(prop-2-enoyl)-2,3,4,4a-tetrahydro-1H-pyrazino[1′,2′:4,5]pyrazino[2,3-c]quinolin-5(6H)-one | 25 | GI | 0 | ALA4404190 | Not Active | Homo sapiens | |||||
| 8. |  MRTX-1719 | 27 | Activity | = | 86 | % | ALA5048089 | % | Homo sapiens | |||
| 9. | MRTX-1719 | 27 | TGI | = | 88 | % | ALA5048088 | % | Homo sapiens | |||
| 10. | MRTX-1719 | 27 | TGI | = | 86 | % | ALA5048087 | % | Homo sapiens | |||
| 11. |  ALA65 | Camptothecin | IC50 | = | 0.001 | ug ml-1 | ALA715191 | ug.mL-1 | Homo sapiens | |||
| 12. |  Paclitaxel | Paclitaxel | IC50 | = | 0.002 | ug ml-1 | ALA715191 | ug.mL-1 | Homo sapiens | |||
| 13. |  Mitomycin C | 1, Mitomycin C (MMC) | IC50 | = | 0.01 | ug ml-1 | ALA715191 | ug.mL-1 | Homo sapiens | |||
| 14. |  ALA11359 | Cisplatin | IC50 | = | 0.001 | ug ml-1 | ALA715191 | ug.mL-1 | Homo sapiens | |||
| 15. |  ALA53463 | Adriamycin | IC50 | = | 0.002 | ug ml-1 | ALA715191 | ug.mL-1 | Homo sapiens | |||
| 16. |  ALA2368220 | 1 | IC50 | = | 0 | ug ml-1 | ALA715191 | ug.mL-1 | Homo sapiens |
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