Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	BFH772	1	IC50	>	0.5	uM	ALA5252780		nM	Homo sapiens
2.	BAW2881(NVP-BAW2881)	2	IC50	>	0.5	uM	ALA5252780		nM	Homo sapiens
3.	ALA3932338	BDBM250054	Ratio IC50	>	2000		ALA5251991			Homo sapiens
4.	tolebrutinib	TOLEBRUTINIB	IC50	=	74	nM	ALA5251928	7.13	nM	Homo sapiens
5.	Branebrutinib (BMS-986195)	BRANEBRUTINIB	IC50	>	10000	nM	ALA5251928		nM	Homo sapiens
6.	Evobrutinib (M-2951)	Evobrutinib	IC50	>	10000	nM	ALA5251928		nM	Homo sapiens
7.	tirabrutinib	TIRABRUTINIB	IC50	>	10000	nM	ALA5251928		nM	Homo sapiens
8.	Orelabrutinib (ICP-022)	ORELABRUTINIB	IC50	=	5900	nM	ALA5251928	5.23	nM	Homo sapiens
9.	Acalabrutinib (ACP-196)	ACALABRUTINIB	IC50	>	10000	nM	ALA5251928		nM	Homo sapiens
10.	Ibrutinib (PCI-32765)	SID124898784	IC50	=	170	nM	ALA5251928	6.77	nM	Homo sapiens
11.	(±)-Zanubrutinib	BDBM249900	IC50	=	370	nM	ALA5251928	6.43	nM	Homo sapiens
12.	ALA5288751	(S)-24a	IC50	>	10000	nM	ALA5251928		nM	Homo sapiens
13.	ALA5276374	(S)-20a; BGB-8035	IC50	>	10000	nM	ALA5251928		nM	Homo sapiens
14.	ALA5276374	(S)-20a; BGB-8035	IC50	=	621	nM	ALA5251914	6.21	nM	Homo sapiens
15.	ALA5267491	24	Imax	<	50	%	ALA5251902		%	Homo sapiens
16.	ALA5278071	23	Imax	<	50	%	ALA5251902		%	Homo sapiens
17.	ALA5271932	22	Imax	<	50	%	ALA5251902		%	Homo sapiens
18.	ALA5269683	21	Imax	<	50	%	ALA5251902		%	Homo sapiens
19.	ALA3932338	BDBM250054	IC50	=	2613	nM	ALA5251900	5.58	nM	Homo sapiens
20.	ALA5272404	36	IC50	=	64	nM	ALA5251900	7.19	nM	Homo sapiens