# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4750435 | 45 | IC50 | > | 100 | uM | ALA4712040 | nM | Homo sapiens | |||
2. | ALA4092230 | Table 1, Entry 13-Lead | IC50 | = | 80 | nM | ALA4668628 | 7.10 | nM | Homo sapiens | ||
3. | ALA3647424 | BDBM139995 | IC50 | = | 6.1 | uM | ALA4668628 | 5.21 | nM | Homo sapiens | ||
4. | 1-Formylpyrrolidine | Entry no. 20-2 | IC50 | > | 5 | mM | ALA4668628 | nM | Homo sapiens | |||
5. | 3'-Aminoacetophenone | 2 | IC50 | > | 5 | mM | ALA4668628 | nM | Homo sapiens | |||
6. | ALA3344501 | 33 | Kd | = | 1.2 | nM | ALA3389005 | 8.92 | nM | Homo sapiens | ||
7. | Cyclosporin A, 8-((2R)-2-((2-(dimethylamino)ethyl)thio)-N-methylglycine)-9-(4-hydroxy-N-methyl-L-leucine)- | 3k | Kd | = | 2.9 | nM | ALA3389005 | 8.54 | nM | Homo sapiens | ||
8. | Alisporivir | Debio 025 | Kd | = | 1 | nM | ALA3389005 | 9.00 | nM | Homo sapiens | ||
9. | NIM811 | NIM811 | Kd | = | 7.4 | nM | ALA3389005 | 8.13 | nM | Homo sapiens | ||
10. | ALA2424822 | 4 | Ki | = | 35.2 | nM | ALA2428072 | 7.45 | nM | Homo sapiens | ||
11. | Cyclosporin A | 1a Cys-A | Kd | = | 5.8 | 10'-3/s | ALA3756834 | 10'-3/s | Homo sapiens | |||
12. | ALA3752642 | 25 | Kd | = | 8.25 | 10'-4/s | ALA3756834 | 10'-4/s | Homo sapiens | |||
13. | Cyclosporin A | 1a Cys-A | Ka | = | 2.7 | 10'3/M/s | ALA3756834 | 10'3/M/s | Homo sapiens | |||
14. | ALA3752642 | 25 | Ka | = | 455.3 | /M/s | ALA3756834 | /M/s | Homo sapiens | |||
15. | ALA3752642 | 25 | Kd | = | 4.5 | 10'-4/s | ALA3756832 | 10'-4/s | Homo sapiens | |||
16. | ALA3752642 | 25 | Ka | = | 213 | /M/s | ALA3756832 | /M/s | Homo sapiens | |||
17. | ALA3752642 | 25 | Kd | = | 2.1 | nM | ALA3756832 | 8.68 | nM | Homo sapiens | ||
18. | ALA3647430 | BDBM140001 | IC50 | = | 1200 | nM | ALA3705673 | 5.92 | 274991 | nM | Homo sapiens | |
19. | ALA3647429 | BDBM140000 | IC50 | = | 5200 | nM | ALA3705673 | 5.28 | 274990 | nM | Homo sapiens | |
20. | ALA3647426 | BDBM139997 | IC50 | = | 24600 | nM | ALA3705673 | 4.61 | 274987 | nM | Homo sapiens |