# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1613766 | F | PUBCHEM_BIOASSAY: Discovery of a Highly Selective in vitro and in vivo M4 Positive Allosteric Modulator(PAM): Activity with human M4. (Class of assay: confirmatory) | Rattus norvegicus | 4 | ALA1201862 | organism-based format | PubChem BioAssays | |
2. | ALA2060896 | A | Plasma clearance in rat | Rattus norvegicus | 3 | ALA2057082 | organism-based format | Scientific Literature | |
3. | ALA2320371 | B | Positive allosteric modulation of rat muscarinic M4 receptor assessed as acetylcholine response | Rattus norvegicus | 4 | ALA2311451 | single protein format | Scientific Literature | |
4. | ALA2320373 | F | Positive allosteric modulation of human muscarinic M4 receptor expressed in CHO-K1 cells assessed as leftward shift in acetylcholine response treated for 144 secs prior to acetylcholine addition measured for 5 mins by Fluo-4-AM based calcium mobilization assay | Homo sapiens | 39 | ALA2311451 | cell-based format | Scientific Literature | |
5. | ALA4309932 | B | Positive allosteric modulation of rat M4 AchR | Rattus norvegicus | 2 | ALA4308844 | single protein format | Scientific Literature | |
6. | ALA4309933 | B | Positive allosteric modulation of human M4 AchR | Homo sapiens | 1 | ALA4308844 | single protein format | Scientific Literature |