| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1614249 | B | PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] | Equus caballus | 42,059 | ALA1201862 | single protein format | PubChem BioAssays | |
| 2. | ALA1614530 | F | PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] | Escherichia coli | 61,607 | ALA1201862 | assay format | PubChem BioAssays | |
| 3. | ALA1613792 | F | PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature. (Class of assay: confirmatory) | Homo sapiens | 3,280 | ALA1201862 | assay format | PubChem BioAssays | |
| 4. | ALA1613992 | F | PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature. (Class of assay: confirmatory) | Homo sapiens | 10,316 | ALA1201862 | assay format | PubChem BioAssays | |
| 5. | ALA1613995 | F | PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature. (Class of assay: confirmatory) [Related pubchem assays: 902 ] | Homo sapiens | 6,267 | ALA1201862 | assay format | PubChem BioAssays | |
| 6. | ALA1614146 | F | PUBCHEM_BIOASSAY: qHTS Assay for Modulators of miRNAs and/or Inhibitors of miR-21. (Class of assay: confirmatory) | Homo sapiens | 31,975 | ALA1201862 | assay format | PubChem BioAssays | |
| 7. | ALA1613836 | F | PUBCHEM_BIOASSAY: qHTS Assay for Modulators of miRNAs and/or Activators of miR-21. (Class of assay: confirmatory) | Homo sapiens | 31,975 | ALA1201862 | assay format | PubChem BioAssays | |
| 8. | ALA1738184 | F | PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] | Homo sapiens | 77,876 | ALA1201862 | assay format | PubChem BioAssays | |
| 9. | ALA1777498 | B | Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-dUTP incorporation into DNA strand by rapid plate assay | Vaccinia virus | 28 | ALA1773050 | single protein format | Scientific Literature | |
| 10. | ALA1777499 | A | Cytotoxicity against african green monkey BSC1 cells infected with Vaccinia virus assessed as lactate dehydrogenase release after 20 hrs by microplate reader | Chlorocebus aethiops | 28 | ALA1773050 | cell-based format | Scientific Literature | |
| 11. | ALA1777500 | B | Binding affinity at Vaccinia virus WR strain D4 assessed as change in unfolding transition temperature at 50 uM by thermofluor method | Vaccinia virus WR | 27 | ALA1773050 | single protein format | Scientific Literature | |
| 12. | ALA1777502 | F | Antiviral activity against Vaccinia virus infected in BSC-1 cells by plaque reduction assay | Vaccinia virus | 28 | ALA1773050 | organism-based format | Scientific Literature | |
| 13. | ALA1777503 | T | Selectivity index, CC50 for African green monkey BSC-1 cells to EC50 for Vaccinia virus | 22 | ALA1773050 | cell-based format | Scientific Literature | ||
| 14. | ALA1777504 | B | Binding affinity at Vaccinia virus WR strain D4 assessed as melting temperature at 50 uM by thermofluor method (Rvb = 38.4 +/- 1.6 degC) | Vaccinia virus WR | 27 | ALA1773050 | single protein format | Scientific Literature | |
| 15. | ALA1794352 | F | PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] | 59,860 | ALA1201862 | assay format | PubChem BioAssays | ||
| 16. | ALA1794483 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] | 114,923 | ALA1201862 | assay format | PubChem BioAssays | ||
| 17. | ALA1794486 | F | PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] | 10,834 | ALA1201862 | assay format | PubChem BioAssays | ||
| 18. | ALA1794536 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] | 7,413 | ALA1201862 | assay format | PubChem BioAssays | ||
| 19. | ALA1794585 | F | PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) | 35,474 | ALA1201862 | assay format | PubChem BioAssays | ||
| 20. | ALA2114713 | F | PubChem BioAssay. qHTS Assay for Activators of ClpP. (Class of assay: confirmatory) | Bacillus subtilis | 20,646 | ALA1201862 | assay format | PubChem BioAssays |
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