# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA693553 | F | Effective concentration necessary to decrease extracellular Hepatitis B virus DNA levels by 50% in human hepatoblastoma cell line (2.2.15 cells) in vitro | Homo sapiens | 4 | ALA1130525 | cell-based format | Scientific Literature | |
2. | ALA693554 | F | Effective concentration necessary to decrease extracellular Hepatitis B virus DNA levels by 90% in human hepatoblastoma cell line (2.2.15 cells) in vitro | Homo sapiens | 4 | ALA1130525 | cell-based format | Scientific Literature | |
3. | ALA693555 | F | Cytotoxicity towards human hepatoblastoma cell line (2.2.15 cells) measured by inhibition of neutral red dye uptake in vitro | Homo sapiens | 4 | ALA1130525 | cell-based format | Scientific Literature | |
4. | ALA693556 | F | Relative level of HBV viral DNA (Extracellular) following treatment of human hepatoblastoma cell line (2.2.15 cells) with the compound | Homo sapiens | 2 | ALA1130525 | cell-based format | Scientific Literature | |
5. | ALA693557 | F | Relative level of HBV viral DNA (Intracellular) following treatment of human hepatoblastoma cell line (2.2.15 cells) with the compound | Homo sapiens | 2 | ALA1130525 | cell-based format | Scientific Literature | |
6. | ALA692959 | F | Relative level of HBV viral antigen (HBcAg) following treatment of human hepatoblastoma cell line (2.2.15 cells) with the compound | Homo sapiens | 2 | ALA1130525 | cell-based format | Scientific Literature | |
7. | ALA692960 | F | Relative level of HBV viral antigen (HBeAg) following treatment of human hepatoblastoma cell line (2.2.15 cells) with the compound | Homo sapiens | 2 | ALA1130525 | cell-based format | Scientific Literature | |
8. | ALA692961 | F | Relative level of HBV viral antigen (HBsAg) following treatment of human hepatoblastoma cell line (2.2.15 cells) with the compound | Homo sapiens | 2 | ALA1130525 | cell-based format | Scientific Literature | |
9. | ALA692962 | F | Relative level of HBV viral mRNA (2.1 kb mRNA) following treatment of human hepatoblastoma cell line (2.2.15 cells) with the compound | Homo sapiens | 2 | ALA1130525 | cell-based format | Scientific Literature | |
10. | ALA693125 | F | Relative level of HBV viral mRNA (3.6 kb mRNA) following treatment of human hepatoblastoma cell line (2.2.15 cells) with the compound | Homo sapiens | 2 | ALA1130525 | cell-based format | Scientific Literature | |
11. | ALA748925 | F | Antituberculosis activity against Mycobacterium tuberculosis at a concentration of 12.5 ug/mL | Mycobacterium tuberculosis | 28 | ALA1133902 | organism-based format | Scientific Literature | |
12. | ALA848428 | F | In vitro selectivity index measured for IC50 to that of EC90 was determined in human hepatoblastoma cell line (2.2.15 cells) | 4 | ALA1130525 | assay format | Scientific Literature | ||
13. | ALA945949 | F | Inhibition of UVB irradiation-induced MMP1 production in human dermal fibroblasts at 5 uM after 48 hrs | Homo sapiens | 5 | ALA1142306 | cell-based format | Scientific Literature | |
14. | ALA945951 | F | Inhibition of UVB irradiation-induced MMP1 production in human dermal fibroblasts at 1.25 uM after 48 hrs | Homo sapiens | 2 | ALA1142306 | cell-based format | Scientific Literature | |
15. | ALA945952 | F | Inhibition of UVB irradiation-induced MMP1 production in human dermal fibroblasts at 2.5 uM after 48 hrs | Homo sapiens | 2 | ALA1142306 | cell-based format | Scientific Literature | |
16. | ALA945961 | B | Inhibition of MMP2 in UVB irradiated human dermal fibroblasts at <5 uM by zymography | Homo sapiens | 5 | ALA1142306 | single protein format | Scientific Literature | |
17. | ALA991974 | B | Inhibition of HIV1 recombinant reverse transcriptase p66/p51 expressed in Escherichia coli | Human immunodeficiency virus 1 | 18 | ALA1158321 | assay format | Scientific Literature | |
18. | ALA991975 | B | Inhibition of HIV1 recombinant reverse transcriptase p66/p51 expressed in Escherichia coli at 200 ug/mL | Human immunodeficiency virus 1 | 16 | ALA1158321 | assay format | Scientific Literature | |
19. | ALA991976 | F | Antiviral activity against HIV1 LAV-1 in PHA-stimulated human PBMC after 6 days | Human immunodeficiency virus 1 | 7 | ALA1158321 | organism-based format | Scientific Literature | |
20. | ALA991977 | A | Cytotoxicity against uninfected PHA-stimulated human PBMC assessed as thymidine incorporation after 24 hrs by trypan blue exclusion method | Homo sapiens | 7 | ALA1158321 | cell-based format | Scientific Literature |