| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1614249 | B | PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] | Equus caballus | 42,059 | ALA1201862 | single protein format | PubChem BioAssays | |
| 2. | ALA1614250 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] | Homo sapiens | 20,446 | ALA1201862 | assay format | PubChem BioAssays | |
| 3. | ALA1614502 | F | PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] | 23,781 | ALA1201862 | assay format | PubChem BioAssays | ||
| 4. | ALA1613769 | F | PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] | Trypanosoma cruzi | 28,016 | ALA1201862 | assay format | PubChem BioAssays | |
| 5. | ALA1777498 | B | Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-dUTP incorporation into DNA strand by rapid plate assay | Vaccinia virus | 28 | ALA1773050 | single protein format | Scientific Literature | |
| 6. | ALA1777499 | A | Cytotoxicity against african green monkey BSC1 cells infected with Vaccinia virus assessed as lactate dehydrogenase release after 20 hrs by microplate reader | Chlorocebus aethiops | 28 | ALA1773050 | cell-based format | Scientific Literature | |
| 7. | ALA1777500 | B | Binding affinity at Vaccinia virus WR strain D4 assessed as change in unfolding transition temperature at 50 uM by thermofluor method | Vaccinia virus WR | 27 | ALA1773050 | single protein format | Scientific Literature | |
| 8. | ALA1777502 | F | Antiviral activity against Vaccinia virus infected in BSC-1 cells by plaque reduction assay | Vaccinia virus | 28 | ALA1773050 | organism-based format | Scientific Literature | |
| 9. | ALA1777503 | T | Selectivity index, CC50 for African green monkey BSC-1 cells to EC50 for Vaccinia virus | 22 | ALA1773050 | cell-based format | Scientific Literature | ||
| 10. | ALA1777504 | B | Binding affinity at Vaccinia virus WR strain D4 assessed as melting temperature at 50 uM by thermofluor method (Rvb = 38.4 +/- 1.6 degC) | Vaccinia virus WR | 27 | ALA1773050 | single protein format | Scientific Literature | |
| 11. | ALA1794440 | F | PUBCHEM_BIOASSAY: qHTS Assay for Substrates of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] | 13,502 | ALA1201862 | assay format | PubChem BioAssays | ||
| 12. | ALA2354221 | F | PubChem BioAssay. qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT. (Class of assay: confirmatory) | 172,532 | ALA1201862 | assay format | PubChem BioAssays | ||
| 13. | ALA2354254 | F | PubChem BioAssay. qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT. (Class of assay: confirmatory) | 153,867 | ALA1201862 | assay format | PubChem BioAssays | ||
| 14. | ALA2354287 | F | PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) | 39,968 | ALA1201862 | assay format | PubChem BioAssays | ||
| 15. | ALA3214953 | F | PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) | 20,285 | ALA1201862 | assay format | PubChem BioAssays |
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