| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1614240 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase). (Class of assay: confirmatory) | Homo sapiens | 5,299 | ALA1201862 | assay format | PubChem BioAssays | |
| 2. | ALA1614249 | Binding | PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] | Equus caballus | 42,059 | ALA1201862 | single protein format | PubChem BioAssays | |
| 3. | ALA1614257 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) | Homo sapiens | 37,649 | ALA1201862 | assay format | PubChem BioAssays | |
| 4. | ALA1614275 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia. (Class of assay: confirmatory) [Related pubchem assays: 2472, 2464 ] | Giardia intestinalis | 14,723 | ALA1201862 | assay format | PubChem BioAssays | |
| 5. | ALA1613821 | Functional | PUBCHEM_BIOASSAY: Confirmation Assay for Inhibitors of Human Galactosidase (GALK). (Class of assay: confirmatory) [Related pubchem assays: 1868, 1379 ] | Homo sapiens | 129 | ALA1201862 | assay format | PubChem BioAssays | |
| 6. | ALA1613910 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4. (Class of assay: confirmatory) | Homo sapiens | 11,728 | ALA1201862 | assay format | PubChem BioAssays | |
| 7. | ALA1614108 | ADME | PUBCHEM_BIOASSAY: qHTS Assay for Activators of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] | Homo sapiens | 6,513 | ALA1201862 | single protein format | PubChem BioAssays | |
| 8. | ALA1614421 | Binding | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] | Homo sapiens | 49,165 | ALA1201862 | single protein format | PubChem BioAssays | |
| 9. | ALA1614502 | Functional | PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] | 23,781 | ALA1201862 | assay format | PubChem BioAssays | ||
| 10. | ALA1613886 | ADME | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] | Homo sapiens | 6,513 | ALA1201862 | single protein format | PubChem BioAssays | |
| 11. | ALA1794311 | Functional | PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] | 20,122 | ALA1201862 | assay format | PubChem BioAssays | ||
| 12. | ALA1794467 | Functional | PUBCHEM_BIOASSAY: Inhibitors of USP1/UAF1: Pilot qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504878] | 1,930 | ALA1201862 | assay format | PubChem BioAssays | ||
| 13. | ALA1794536 | Functional | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] | 7,413 | ALA1201862 | assay format | PubChem BioAssays | ||
| 14. | ALA1613800 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2312, AID2537, AID2702] | Homo sapiens | 6,916 | ALA1201862 | assay format | PubChem BioAssays | |
| 15. | ALA1673974 | Functional | Antiparasitic activity against Ancylostoma caninum isolate NT assessed as compound concentration required to inhibit parasitic contraction by larval arrested morphology assay | Ancylostoma caninum | 4 | ALA1671630 | assay format | Scientific Literature | |
| 16. | ALA1673975 | Functional | Antiparasitic activity against Ancylostoma caninum isolate PR assessed as compound concentration required to inhibit parasitic contraction by larval arrested morphology assay | Ancylostoma caninum | 4 | ALA1671630 | assay format | Scientific Literature | |
| 17. | ALA1673976 | Functional | Ratio of IC50 for Ancylostoma caninum isolate NT to IC50 for Ancylostoma caninum isolate PR by larval arrested morphology assay | Ancylostoma caninum | 4 | ALA1671630 | assay format | Scientific Literature | |
| 18. | ALA1673980 | Functional | Antiparasitic activity against Ancylostoma caninum isolate NT assessed as increase in contraction force at 6 to 500 ug/ml by force transduction assay | Ancylostoma caninum | 1 | ALA1671630 | assay format | Scientific Literature | |
| 19. | ALA1673981 | Functional | Antiparasitic activity against Ancylostoma caninum isolate PR assessed as increase in contraction force at 6 to 500 ug/ml by force transduction assay | Ancylostoma caninum | 1 | ALA1671630 | assay format | Scientific Literature | |
| 20. | ALA1673982 | Functional | Antiparasitic activity against Ancylostoma caninum isolate NT assessed as concentration of drug required to cause a force of contraction half that of the KCl-induced maximal contraction by force transduction assay | Ancylostoma caninum | 4 | ALA1671630 | assay format | Scientific Literature |
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