| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA874036 | B | Tested for inhibition of Escherichia coli gamma-glutamylcysteine synthetase at a concentration of 25.0 uM | Escherichia coli | 1 | ALA1150519 | single protein format | Scientific Literature | |
| 2. | ALA681834 | B | Second order rate constant for time-dependent inhibition (Kinact/Ki) of Escherichia coli gamma-glutamylcysteine synthetase at a concentration of 25.0 uM; Not determined | Escherichia coli | 1 | ALA1150519 | single protein format | Scientific Literature | |
| 3. | ALA682477 | B | Compound was tested for the inhibition of Escherichia coli gamma-glutamylcysteine synthetase at a concentration of 25.0 uM | Escherichia coli | 1 | ALA1150519 | single protein format | Scientific Literature | |
| 4. | ALA931521 | F | Reduction of glutathione synthesis in human MCF7 cells at 25 uM after 25 hrs | Homo sapiens | 1 | ALA1147045 | cell-based format | Scientific Literature | |
| 5. | ALA1262537 | F | Antitrypanosomal activity against Trypanosoma cruzi clone Dm28c metacyclic trypomastigotes infected in BALB/c mouse assessed as increase in survival rate at 220 mg/kg/day, ip measured after 20 days (Rvb = 25%) | Trypanosoma cruzi | 1 | ALA1255344 | organism-based format | Scientific Literature | |
| 6. | ALA1263053 | F | Antitrypanosomal activity against Trypanosoma cruzi clone Dm28c metacyclic trypomastigotes infected in mouse assessed as decrease in heart parasitemia at 220 mg/kg/day, ip measured after 20 days | Trypanosoma cruzi | 1 | ALA1255344 | organism-based format | Scientific Literature | |
| 7. | ALA1263054 | F | Antitrypanosomal activity against Trypanosoma cruzi clone Dm28c metacyclic trypomastigotes infected in mouse assessed as decrease in heart parasite burden at 220 mg/kg/day, ip measured after 20 days | Trypanosoma cruzi | 1 | ALA1255344 | organism-based format | Scientific Literature | |
| 8. | ALA1263055 | T | Toxicity in BALB/c mouse at 220 mg/kg/day, ip measured after 20 days | Mus musculus | 1 | ALA1255344 | organism-based format | Scientific Literature | |
| 9. | ALA1263056 | F | Antitrypanosomal activity against Trypanosoma cruzi clone Dm28c metacyclic trypomastigotes infected in BALB/c mouse assessed as increase in survival rate at 30 mg/kg/day, ip measured after 20 days | Trypanosoma cruzi | 1 | ALA1255344 | organism-based format | Scientific Literature | |
| 10. | ALA1263057 | F | Antitrypanosomal activity against Trypanosoma cruzi clone Dm28c metacyclic trypomastigotes infected in mouse assessed as decrease in heart parasitemia at 30 mg/kg/day, ip measured after 20 days | Trypanosoma cruzi | 1 | ALA1255344 | organism-based format | Scientific Literature | |
| 11. | ALA1263058 | F | Antitrypanosomal activity against Trypanosoma cruzi clone Dm28c metacyclic trypomastigotes infected in mouse assessed as decrease in heart parasite burden at 30 mg/kg/day, ip measured after 20 days | Trypanosoma cruzi | 1 | ALA1255344 | organism-based format | Scientific Literature | |
| 12. | ALA1263186 | F | Antitrypanosomal activity against Trypanosoma cruzi clone Dm28c metacyclic trypomastigotes infected in BALB/c mouse assessed as increase in survival rate at 10 mg/kg/day, ip measured after 20 days | Trypanosoma cruzi | 1 | ALA1255344 | organism-based format | Scientific Literature | |
| 13. | ALA1263187 | F | Antitrypanosomal activity against Trypanosoma cruzi clone Dm28c metacyclic trypomastigotes infected in BALB/c mouse assessed as increase in survival rate at 2.5 mg/kg/day, ip measured after 20 days | Trypanosoma cruzi | 1 | ALA1255344 | organism-based format | Scientific Literature | |
| 14. | ALA1266185 | F | Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay | Mus musculus | 1,252 | ALA1255231 | assay format | Scientific Literature | |
| 15. | ALA1267249 | F | Antiplasmodial activity against Plasmodium falciparum GB4 after 72 hrs by SYBR green assay | Plasmodium falciparum | 567 | ALA1255382 | organism-based format | Scientific Literature | |
| 16. | ALA1267251 | F | Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay | Plasmodium falciparum | 655 | ALA1255382 | organism-based format | Scientific Literature | |
| 17. | ALA1738675 | F | PUBCHEM_BIOASSAY: Validation screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493125, AID504467] | Homo sapiens | 366 | ALA1201862 | assay format | PubChem BioAssays | |
| 18. | ALA1737980 | F | PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors: Validation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493163, AID504444, AID504648] | Homo sapiens | 338 | ALA1201862 | assay format | PubChem BioAssays | |
| 19. | ALA1738442 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] | Homo sapiens | 90,358 | ALA1201862 | assay format | PubChem BioAssays | |
| 20. | ALA1614279 | F | PUBCHEM_BIOASSAY: qHTS Validation Assay to Find Inhibitors of T. brucei phosphofructokinase. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488768, AID492961] | Trypanosoma brucei | 647 | ALA1201862 | assay format | PubChem BioAssays |
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