| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1646987 | B | Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assay | Homo sapiens | 29 | ALA1641603 | single protein format | Scientific Literature | |
| 2. | ALA1646988 | B | Inhibition of Candida albicans recombinant beta-carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assay | Candida albicans | 29 | ALA1641603 | assay format | Scientific Literature | |
| 3. | ALA1646989 | B | Inhibition of Mycobacterium tuberculosis recombinant beta-carbonic anhydrase Rv1284 preincubated for 15 mins by stopped-flow CO2 hydrase assay | Mycobacterium tuberculosis | 29 | ALA1641603 | single protein format | Scientific Literature | |
| 4. | ALA1646990 | B | Inhibition of Mycobacterium tuberculosis recombinant beta-carbonic anhydrase Rv3273 preincubated for 15 mins by stopped-flow CO2 hydrase assay | Mycobacterium tuberculosis | 29 | ALA1641603 | single protein format | Scientific Literature | |
| 5. | ALA1646991 | B | Selectivity ratio, ratio of Ki for human recombinant carbonic anhydrase 2 to Ki for Candida albicans recombinant beta-carbonic anhydrase | 2 | ALA1641603 | assay format | Scientific Literature | ||
| 6. | ALA1646992 | B | Selectivity ratio, ratio of Ki for Mycobacterium tuberculosis recombinant beta-carbonic anhydrase Rv1284 to Ki for Candida albicans recombinant beta-carbonic anhydrase | 3 | ALA1641603 | assay format | Scientific Literature | ||
| 7. | ALA1646993 | B | Selectivity ratio, ratio of Ki for Mycobacterium tuberculosis recombinant beta-carbonic anhydrase Rv3273 to Ki for Candida albicans recombinant beta-carbonic anhydrase | 3 | ALA1641603 | assay format | Scientific Literature | ||
| 8. | ALA1693044 | B | Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 min by CO2 hydration assay | Homo sapiens | 28 | ALA1687939 | single protein format | Scientific Literature | |
| 9. | ALA1693045 | B | Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 min by CO2 hydration assay | Homo sapiens | 28 | ALA1687939 | single protein format | Scientific Literature | |
| 10. | ALA1693046 | B | Inhibition of tumor-associated human carbonic anhydrase 9 preincubated for 15 min by CO2 hydration assay | Homo sapiens | 28 | ALA1687939 | single protein format | Scientific Literature | |
| 11. | ALA1693047 | B | Inhibition of tumor-associated human carbonic anhydrase 12 preincubated for 15 min by CO2 hydration assay | Homo sapiens | 28 | ALA1687939 | single protein format | Scientific Literature | |
| 12. | ALA1693050 | F | Antimetastatic activity against mouse 4T1 cells expressing luciferase xenografted in BALB/c mouse assessed as limiting colonization of the cells in the lungs at 15 to 45 mg/kg, ip administered as 3 doses on alternate days measured 24 hrs post last dose by bioluminescent technique relative to control | Mus musculus | 1 | ALA1687939 | organism-based format | Scientific Literature | |
| 13. | ALA1693051 | T | Toxicity in BALB/c mouse assessed as body weight loss at 15 to 45 mg/kg, ip qd administered as 3 doses on alternate days | Mus musculus | 1 | ALA1687939 | organism-based format | Scientific Literature | |
| 14. | ALA2379886 | B | Inhibition of recombinant full length Candida glabrata NCE103 expressed in Escherichia coli BL21 preincubated for 15 mins by stopped-flow CO2 hydrase assay | Nakaseomyces glabratus | 62 | ALA2375327 | assay format | Scientific Literature | |
| 15. | ALA2379887 | B | Inhibition of Cryptococcus neoformans Can2 expressed in Candida albicans RH1 preincubated for 15 mins by stopped-flow CO2 hydrase assay | Cryptococcus neoformans | 27 | ALA2375327 | assay format | Scientific Literature | |
| 16. | ALA2443607 | B | Inhibition of human CA12 by stopped-flow CO2 hydrase assay | Homo sapiens | 5 | ALA2439959 | single protein format | Scientific Literature | |
| 17. | ALA2443608 | B | Inhibition of human CA5B by stopped-flow CO2 hydrase assay | Homo sapiens | 5 | ALA2439959 | single protein format | Scientific Literature | |
| 18. | ALA2443609 | B | Inhibition of human CA9 by stopped-flow CO2 hydrase assay | Homo sapiens | 5 | ALA2439959 | single protein format | Scientific Literature | |
| 19. | ALA2443610 | B | Inhibition of human CA2 by stopped-flow CO2 hydrase assay | Homo sapiens | 1 | ALA2439959 | single protein format | Scientific Literature | |
| 20. | ALA2443611 | B | Inhibition of human CA5A by stopped-flow CO2 hydrase assay | Homo sapiens | 5 | ALA2439959 | single protein format | Scientific Literature |
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