# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4689086 | B | Antagonist activity at P2X7R in mouse N2a cells assessed as inhibition of ATP-induced ROS production at 50 uM incubated for 1 hr by using H2DCF-DA probe based fluorescence assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
2. | ALA4689093 | B | Antagonist activity at P2X7R in mouse N2a cells assessed as inhibition of ATP-induced NO production at 50 uM incubated for 1 hr by using DAF-FM probe based fluorescence assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
3. | ALA4689097 | B | Antagonist activity at P2X7R in mouse N2a cells assessed as reduction in ATP-induced calcium influx at 50 uM incubated for 1 hr by Fura-2AM dye based spectrofluorometry | Mus musculus | 1 | cell-based format | Scientific Literature | ||
4. | ALA5134925 | F | Cytotoxicity against human 1321N1 cells assessed as reduction in cell viability at 50 uM incubated for 24 hrs by MTT assay relative to control | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
5. | ALA5134926 | T | Cytotoxicity against human HEK293 cells assessed as reduction in cell viability at 50 uM incubated for 24 hrs by MTT assay relative to control | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
6. | ALA5134927 | F | Cytotoxicity against human HeLa cells assessed as reduction in cell viability at 50 uM incubated for 24 hrs by MTT assay relative to control | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
7. | ALA5134928 | B | Antagonist activity at human P2X2 receptor expressed in human 1321N1 cells assessed as reduction in intracellular Ca2+ influx incubated for 30 mins by Fura-2 AM based fluorescence assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
8. | ALA5134929 | B | Antagonist activity at human P2X4 receptor expressed in human 1321N1 cells assessed as reduction in intracellular Ca2+ influx incubated for 30 mins by Fura-2 AM based fluorescence assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
9. | ALA5134930 | B | Antagonist activity at human P2X5 receptor expressed in human 1321N1 cells assessed as reduction in intracellular Ca2+ influx incubated for 30 mins by Fura-2 AM based fluorescence assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
10. | ALA5134935 | B | Antagonist activity at human P2X7 receptor expressed in human 1321N1 cells assessed as reduction in intracellular Ca2+ influx incubated for 30 mins by Fura-2 AM based fluorescence assay relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature |