# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2095143 | Toxicity | DNDI: Cytotoxicity against human MRC-5 lung fibroblast cells. | Homo sapiens | 655 | ALA2094269 | cell-based format | Drugs for Neglected Diseases Initiative (DNDi) | |
2. | ALA2095144 | Functional | DNDI: Inhibition of Human African Trypanosomiasis (HAT), STIB 795, in vitro | Trypanosoma brucei brucei | 1,148 | ALA2094269 | organism-based format | Drugs for Neglected Diseases Initiative (DNDi) | |
3. | ALA5119572 | Binding | Inhibition of human OCT3 mediated (S,S)-Ethambutol uptake overexpressed in HEK293 cells at 20 uM incubated for 5 mins by HPLC-MS/MS analysis relative to control | Homo sapiens | 4 | ALA5113524 | cell-based format | Scientific Literature | |
4. | ALA5119573 | Binding | Inhibition of human OCT3 mediated Famotidine uptake overexpressed in HEK293 cells at 20 uM incubated for 5 mins by HPLC-MS/MS analysis relative to control | Homo sapiens | 4 | ALA5113524 | cell-based format | Scientific Literature | |
5. | ALA5119574 | Binding | Inhibition of human OCT3 mediated N-Ethyllidocaine uptake overexpressed in HEK293 cells at 20 uM incubated for 5 mins by HPLC-MS/MS analysis relative to control | Homo sapiens | 4 | ALA5113524 | cell-based format | Scientific Literature | |
6. | ALA5119575 | Binding | Inhibition of human OCT3 mediated methylscopolamine uptake overexpressed in HEK293 cells at 20 uM incubated for 5 mins by HPLC-MS/MS analysis relative to control | Homo sapiens | 5 | ALA5113524 | cell-based format | Scientific Literature | |
7. | ALA5119578 | ADME | Substrate uptake at human OCT3 overexpressed in HEK293 cells incubated for 2 mins by LC-MS/MS analysis | Homo sapiens | 5 | ALA5113524 | cell-based format | Scientific Literature | |
8. | ALA5119579 | ADME | Substrate uptake in empty vector transfected (OCT3 null) HEK293 cells incubated for 2 mins by LC-MS/MS analysis | Homo sapiens | 5 | ALA5113524 | cell-based format | Scientific Literature |