The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
The page will load shortly, Thanks for your patience!
# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA2095143 T DNDI: Cytotoxicity against human MRC-5 lung fibroblast cells. Homo sapiens 655 ALA2094269 cell-based format Drugs for Neglected Diseases Initiative (DNDi) 2. ALA2095144 F DNDI: Inhibition of Human African Trypanosomiasis (HAT), STIB 795, in vitro Trypanosoma brucei brucei 1,148 ALA2094269 organism-based format Drugs for Neglected Diseases Initiative (DNDi) 3. ALA3301363 P ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake flask method described in J. Biomol. Screen. 2011, 16, 348-355. Experimental range -1.5 to 4.5 4,197 ALA3301361 small-molecule physicochemical format AstraZeneca Deposited Data 4. ALA3301364 P ASTRAZENECA: Solubility in pH7.4 buffer using solid starting material using the method described in J. Assoc. Lab. Autom. 2011, 16, 276-284. Experimental range 0.10 to 1500 uM 1,763 ALA3301361 small-molecule physicochemical format AstraZeneca Deposited Data 5. ALA3881261 P Lipophilicity, log P of the compound 152 ALA3880431 small-molecule physicochemical format Patent Bioactivity Data 6. ALA3881262 B Binding affinity to Neisseria meningitidis wild type apo heme oxygenase expressed in Escherichia coli BL21(DE3) pLysS by spectrofluorimetric analysis Neisseria meningitidis 89 ALA3880431 assay format Patent Bioactivity Data 7. ALA3881263 B Binding affinity to Pseudomonas aeruginosa MPAO1 wild type apo heme oxygenase by spectrofluorimetric analysis Pseudomonas aeruginosa 89 ALA3880431 single protein format Patent Bioactivity Data 8. ALA3881264 B Binding affinity to Pseudomonas aeruginosa MPAO1 wild type apo heme oxygenase by NMR analysis Pseudomonas aeruginosa 79 ALA3880431 single protein format Patent Bioactivity Data 9. ALA3881265 B Inhibition of Neisseria meningitidis heme oxygenase expressed in Escherichia coli BL21(DE3) cells assessed as decrease in alpha-biliverdin production at 1500 uM after 16 hrs by HPLC analysis Neisseria meningitidis 31 ALA3880431 cell-based format Patent Bioactivity Data 10. ALA3881279 F Antimicrobial activity against Pseudomonas aeruginosa MPAO1 after 10 hrs Pseudomonas aeruginosa 87 ALA3880431 assay format Patent Bioactivity Data 11. ALA3881280 P Solubility of the compound in methanol 50 ALA3880431 small-molecule physicochemical format Patent Bioactivity Data