# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2215079 | Binding | Displacement of [125I]-CCL3 from human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrs | Homo sapiens | 22 | ALA2203007 | cell-based format | Scientific Literature | |
2. | ALA2215081 | Binding | Displacement of [125I]-CCL3 from human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrs | Homo sapiens | 22 | ALA2203007 | cell-based format | Scientific Literature | |
3. | ALA2215082 | Functional | Allosteric modulation at human CCR8 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation counting analysis relative to basal level | Homo sapiens | 17 | ALA2203007 | cell-based format | Scientific Literature | |
4. | ALA2215083 | Functional | Ratio of ZnPhe EC50 to compound EC50 for human CCR8 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as IP3 turnover by liquid scintillation counting analysis | Homo sapiens | 9 | ALA2203007 | cell-based format | Scientific Literature | |
5. | ALA2215085 | Physicochemical | Binding affinity to Zn(II) after 2 hrs using FluoZin-3 by fuorescence assay | 22 | ALA2203007 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA2215086 | Functional | Allosteric modulation at human CCR8 transfected in COS7 cells assessed as [3H]IP3 turnover by liquid scintillation counting analysis | Homo sapiens | 22 | ALA2203007 | cell-based format | Scientific Literature | |
7. | ALA2215087 | Functional | Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation counting analysis | Homo sapiens | 22 | ALA2203007 | cell-based format | Scientific Literature | |
8. | ALA2215088 | Functional | Allosteric modulation at human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as {3H]IP3 turnover by liquid scintillation counting analysis | Homo sapiens | 22 | ALA2203007 | cell-based format | Scientific Literature | |
9. | ALA4888485 | Functional | Primary screen in NF54 nanoGlo assay, in single point, at 2uM, 72h | Plasmodium falciparum | 147,432 | ALA4888484 | organism-based format | MMV Malaria HGL |