| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1803421 | A | Cytotoxicity against TRAIL-resistant human MDA-MB-231 cells assessed as induction of apoptosis by CellTiter-Glo luminescent assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA1803422 | B | Competitive inhibition of XIAP BIR2 domain by fluorescent polarization assay | 32 | single protein format | Scientific Literature | |||
| 3. | ALA1803423 | B | Competitive inhibition of XIAP BIR3 domain by fluorescent polarization assay | 32 | single protein format | Scientific Literature | |||
| 4. | ALA1803515 | F | Sensitization of TRAIL-induced apoptosis in TRAIL-resistant human MDA-MB-231 cells assessed as cell viability compound pre-treated for 4 hrs before TRAIL challenge measured after 20 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA1803516 | B | Selectivity ratio of Ki for XIAP BIR3 domain to Ki for XIAP BIR2 domain | 13 | single protein format | Scientific Literature | |||
| 6. | ALA2406562 | A | Cytotoxicity against human HFF cells at 5 uM in presence of TRAIL | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA2406564 | A | Cytotoxicity against human HFF cells at 5 uM | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA2406565 | F | Induction of apoptosis in TRAIL-resistant human MDA-MB-231 cells in presence of TNF | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA2406566 | F | Induction of apoptosis in TRAIL-resistant human PPC1 cells incubated for 4 hrs prior to TRAIL addition measured after 20 hrs by ATPlite assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA2406569 | B | Selectivity ratio of Ki for XIAP-BIR3 domain (unknown origin) to Ki for XIAP-BIR2 domain (unknown origin) | Homo sapiens | 20 | single protein format | Scientific Literature | ||
| 11. | ALA2406570 | B | Competitive inhibition of XIAP-BIR3 domain (unknown origin) by fluorescence polarization assay | Homo sapiens | 29 | single protein format | Scientific Literature | ||
| 12. | ALA2406571 | B | Competitive inhibition of XIAP-BIR2 domain (unknown origin) by fluorescence polarization assay | Homo sapiens | 29 | single protein format | Scientific Literature |
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