# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA640164 | A | Half-life was determined | 5 | ALA1125792 | assay format | Scientific Literature | ||
2. | ALA641946 | A | Rate constant for loss of chromophore | 5 | ALA1125792 | assay format | Scientific Literature | ||
3. | ALA766558 | F | Vasorelaxant activity against isolated vascular ring preparation from rabbit thoracic aorta | Oryctolagus cuniculus | 5 | ALA1125792 | organism-based format | Scientific Literature | |
4. | ALA766560 | F | Peak relaxation(Rm) of the vascular ring by the compound at highest concentration | Oryctolagus cuniculus | 5 | ALA1125792 | organism-based format | Scientific Literature | |
5. | ALA1687466 | F | Vasodilatory activity in Sprague-Dawley rat thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction at 0.01 nM to 100 uM | Rattus norvegicus | 4 | ALA1681634 | tissue-based format | Scientific Literature | |
6. | ALA1687467 | F | Vasodilatory activity in Sprague-Dawley rat thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction compound treated 5 mins after 1 uM soluble guanylate cyclase inhibitor ODQ treatment | Rattus norvegicus | 4 | ALA1681634 | tissue-based format | Scientific Literature | |
7. | ALA1687468 | F | Vasodilatory activity in Sprague-Dawley rat thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction compound treated 5 mins after 200 uM NO-scavenger C-PTIO treatment | Rattus norvegicus | 4 | ALA1681634 | tissue-based format | Scientific Literature | |
8. | ALA1687469 | F | Vasodilatory activity in Sprague-Dawley rat thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction at 0.01 nM to 1 uM in presence of 21% oxygen | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
9. | ALA1687470 | F | Vasodilatory activity in Sprague-Dawley rat thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction at 0.01 nM to 1 uM in presence of 1% oxygen | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
10. | ALA1687471 | F | Vasodilatory activity in Sprague-Dawley rat thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction at 0.01 nM to 1 uM in presence 100 U/ml SOD at 21% oxygen | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
11. | ALA1687472 | F | Potentiation of Angeli's salt induced- vasodilatory activity in Sprague-Dawley rat thoracic aorta at 1 mM | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
12. | ALA1687473 | F | Potentiation of 1-Nitrosocyclohexyl trifluoroacetate induced- vasodilatory activity in Sprague-Dawley rat thoracic aorta at 1 mM | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
13. | ALA1687476 | F | Inhibition of Angeli's salt induced- vasodilatory activity in Sprague-Dawley rat thoracic aorta at 0.1 to 1 mM | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
14. | ALA1687477 | F | Inhibition of 1-Nitrosocyclohexyl trifluoroacetate induced- vasodilatory activity in Sprague-Dawley rat thoracic aorta at 0.1 to 1 mM | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
15. | ALA1687479 | F | Vasodilatory activity in rabbit thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction | Oryctolagus cuniculus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
16. | ALA1687480 | F | Vasodilatory activity in bovine intrapulmonary artery assessed as relaxation of phenylephrine-induced vasoconstriction | Bos taurus | 3 | ALA1681634 | assay format | Scientific Literature | |
17. | ALA2182795 | P | Induction of nitroxyl release in 7.5% DMSO and 92.5% phosphate buffer at pH 7.4 at 200 uM after 48 hrs by LC-MS analysis | 7 | ALA2176969 | small-molecule physicochemical format | Scientific Literature | ||
18. | ALA2182796 | P | Induction of nitroxyl release in 7.5% DMSO and 92.5% phosphate buffer at pH 7.4 at 200 uM after 2 hrs by LC-MS analysis | 7 | ALA2176969 | small-molecule physicochemical format | Scientific Literature | ||
19. | ALA2378739 | P | Induction of HNO release in phosphate buffer saline after 48 hrs by phosphine-trapping based LC-MS assay relative to control | 3 | ALA2375329 | small-molecule physicochemical format | Scientific Literature | ||
20. | ALA2378740 | P | Induction of HNO release in phosphate buffer saline after 2 hrs by phosphine-trapping based LC-MS assay relative to control | 3 | ALA2375329 | small-molecule physicochemical format | Scientific Literature |