# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1635193 | B | Antiprion activity against mouse recombinant PrP expressed in Fukuoka-1 stain infected mouse GT1-7 cells assessed as remaining PrP-res level at 10 uM after 72 hrs by Western blotting relative to control | Mus musculus | 27 | cell-based format | Scientific Literature | ||
2. | ALA1635195 | B | Binding affinity to mouse recombinant PrP (121-231) after 10 mins by surface plasmon resonance assay | Mus musculus | 14 | single protein format | Scientific Literature | ||
3. | ALA4179216 | B | Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blot | Mesocricetus auratus | 21 | single protein format | Scientific Literature | ||
4. | ALA4179217 | B | Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by measuring PrPSc level relative to untreated control | Mesocricetus auratus | 22 | single protein format | Scientific Literature |