# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1913487 | B | Antiprion activity in human transmissible spongiform encephalopathies agent Fukuoka-1 prion infected mouse GT1-7 cells assessed as inhibition of proteinase K-resistant PrPres accumulation after 3 days by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
2. | ALA1913513 | B | Antiprion activity in Gerstmann-Straussler-Scheinker syndrome infected mouse ScN2a-3-Ch cells assessed as inhibition of proteinase K-resistant PrPres accumulation at 5 uM after 3 days by Western blot analysis relative to control | Mus musculus | 5 | assay format | Scientific Literature | ||
3. | ALA1635193 | B | Antiprion activity against mouse recombinant PrP expressed in Fukuoka-1 stain infected mouse GT1-7 cells assessed as remaining PrP-res level at 10 uM after 72 hrs by Western blotting relative to control | Mus musculus | 27 | cell-based format | Scientific Literature | ||
4. | ALA1635195 | B | Binding affinity to mouse recombinant PrP (121-231) after 10 mins by surface plasmon resonance assay | Mus musculus | 14 | single protein format | Scientific Literature |