# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1641185 | Binding | Selectivity for Trypanosoma cruzi triosephosphate isomerase over human triosephosphate isomerase | 226 | ALA1629474 | assay format | Scientific Literature | ||
2. | ALA1641186 | Functional | Antiparasitic activity against Trypanosoma cruzi T2 epimastigotes assessed as growth inhibition | Trypanosoma cruzi | 15 | ALA1629474 | organism-based format | Scientific Literature | |
3. | ALA1641187 | Functional | Antiparasitic activity against Trypanosoma cruzi T2 epimastigotes assessed as growth inhibition at 25 uM after 5 days | Trypanosoma cruzi | 227 | ALA1629474 | organism-based format | Scientific Literature | |
4. | ALA1641188 | Binding | Inhibition of Trypanosoma cruzi triosephosphate isomerase after 2 hrs | Trypanosoma cruzi | 5 | ALA1629474 | single protein format | Scientific Literature | |
5. | ALA1641189 | Binding | Inhibition of Trypanosoma cruzi triosephosphate isomerase at 100 uM after 2 hrs | Trypanosoma cruzi | 227 | ALA1629474 | single protein format | Scientific Literature | |
6. | ALA1641190 | Binding | Inhibition of Trypanosoma cruzi triosephosphate isomerase at 400 uM after 2 hrs | Trypanosoma cruzi | 227 | ALA1629474 | single protein format | Scientific Literature | |
7. | ALA1641191 | Binding | Inhibition of human triosephosphate isomerase at 100 uM after 2 hrs | Homo sapiens | 5 | ALA1629474 | single protein format | Scientific Literature | |
8. | ALA3266190 | Binding | Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 mins by fluorescence analysis | Homo sapiens | 14 | ALA3259678 | single protein format | Scientific Literature | |
9. | ALA3266555 | Binding | Ratio of Kinact to Ki for immunoproteasome-20S subunit beta5i in human PBMC using suc-LLVY-AMC as substrate measured for 120 mins by fluorescence analysis | Homo sapiens | 17 | ALA3259678 | single protein format | Scientific Literature | |
10. | ALA3266556 | Binding | Inhibition of constitutive proteasome 20S subunit beta5c in human RBC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 mins by fluorescence analysis | Homo sapiens | 17 | ALA3259678 | assay format | Scientific Literature | |
11. | ALA3266557 | Binding | Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate by fluorescence analysis | Homo sapiens | 10 | ALA3259678 | single protein format | Scientific Literature | |
12. | ALA3266566 | Binding | Ratio of Kinact/Ki for immunoproteasome-20S subunit beta5i in human PBMC to Kinact/Ki for constitutive proteasome 20S subunit beta5c in human RBC | Homo sapiens | 17 | ALA3259678 | assay format | Scientific Literature |