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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA1924373 Binding Inhibition of human IKK2-mediated GST-IkappaBalpha protein fusion phosphorylation Homo sapiens 28 ALA1921674 single protein format Scientific Literature 2. ALA1924374 Functional Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release treated for 5 mins before LPS challenge measured after 4 hrs by ELISA Homo sapiens 27 ALA1921674 cell-based format Scientific Literature 3. ALA1924375 Functional Antiinflammatory activity in human whole blood assessed as inhibition of LPS-induced TNFalpha release treated for 45 mins before LPS challenge measured after 6 hrs by ELISA Homo sapiens 23 ALA1921674 tissue-based format Scientific Literature 4. ALA1646103 Functional Antiinflammatory activity in po dosed BALB/c mouse assessed as inhibition of LPS-induced TNFalpha release administered for 5 hrs before LPS challenge measured after 6.5 hrs post dose by ELISA Mus musculus 2 ALA1641407 organism-based format Scientific Literature 5. ALA1646104 Binding Inhibition at STK16 at 10 uM relative to control 2 ALA1641407 single protein format Scientific Literature 6. ALA1646105 Binding Inhibition at JNK3 at 10 uM relative to control 1 ALA1641407 single protein format Scientific Literature 7. ALA1646106 Binding Inhibition at GAK at 10 uM relative to control 1 ALA1641407 single protein format Scientific Literature 8. ALA1646107 Binding Inhibition at DAPK2 at 10 uM relative to control 2 ALA1641407 single protein format Scientific Literature 9. ALA1646108 Functional Antiinflammatory activity in mouse whole blood assessed as inhibition of LPS-induced TNFalpha release treated for 5 mins before LPS challenge measured after 6 hrs by ELISA Mus musculus 2 ALA1641407 tissue-based format Scientific Literature 10. ALA1646289 ADME Total AUC in dog at 2 mg/kg, iv Canis lupus familiaris 1 ALA1641407 organism-based format Scientific Literature 11. ALA1646290 ADME Total AUC in rat at 2 mg/kg, iv and 10 mg/kg, po Rattus norvegicus 1 ALA1641407 organism-based format Scientific Literature 12. ALA1646291 ADME Total AUC in mouse at 2 mg/kg, iv and 10 mg/kg, po Mus musculus 1 ALA1641407 organism-based format Scientific Literature 13. ALA1646292 ADME Volume of distribution at steady state in dog at 2 mg/kg, iv Canis lupus familiaris 1 ALA1641407 organism-based format Scientific Literature 14. ALA1646293 ADME Volume of distribution at steady state in rat at 2 mg/kg, iv and 10 mg/kg, po Rattus norvegicus 1 ALA1641407 organism-based format Scientific Literature 15. ALA1646294 ADME Volume of distribution at steady state in mouse at 2 mg/kg, iv and 10 mg/kg, po Mus musculus 1 ALA1641407 organism-based format Scientific Literature 16. ALA1646295 ADME Clearance in dog at 2 mg/kg, iv Canis lupus familiaris 1 ALA1641407 organism-based format Scientific Literature 17. ALA1646296 Functional Antiinflammatory activity in human whole blood assessed as inhibition of LPS-induced TNFalpha release treated for 5 mins before LPS challenge measured after 6 hrs by ELISA Homo sapiens 2 ALA1641407 tissue-based format Scientific Literature 18. ALA1646297 ADME Clearance in mouse at 2 mg/kg, iv and 10 mg/kg, po Mus musculus 1 ALA1641407 organism-based format Scientific Literature 19. ALA1646298 ADME Clearance in rat at 2 mg/kg, iv and 10 mg/kg, po Rattus norvegicus 6 ALA1641407 organism-based format Scientific Literature 20. ALA1646299 ADME Mean residence time in rat at 2 mg/kg, iv and 10 mg/kg, po Rattus norvegicus 1 ALA1641407 organism-based format Scientific Literature