| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1932647 | F | Antipsychotic activity in ICR mouse assessed as inhibition of (+)-HA966-induced hyperlocomotion at 10 mg/kg, ip administered 20 mins prior (+)-HA966] challenge measured every 90 mins | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 2. | ALA1932648 | B | Displacement of [3H]glycine from rat GlyT1 expressed in rat C6 cells after 30 mins by scintillation counting | Rattus norvegicus | 19 | cell-based format | Scientific Literature | ||
| 3. | ALA1932649 | B | Displacement of [3H]glycine from Wistar rat brain GlyT2 after 10 mins by scintillation counting | Rattus norvegicus | 9 | assay format | Scientific Literature | ||
| 4. | ALA1932650 | B | Selectivity ratio of IC50 for rat GlyT1 to IC50 for rat GlyT2 | Rattus norvegicus | 8 | assay format | Scientific Literature | ||
| 5. | ALA1932651 | P | Aqueous solubility of the compound at pH 1.2 | 6 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA1932706 | P | Aqueous solubility of the compound at pH 6.8 | 6 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA1657779 | B | Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cells | Rattus norvegicus | 30 | cell-based format | Scientific Literature | ||
| 8. | ALA1657780 | B | Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cells | Rattus norvegicus | 25 | cell-based format | Scientific Literature | ||
| 9. | ALA1657781 | B | Selectivity ratio of IC50 for GlyT2 in rat C6 cells to IC50 for GlyT1 in rat C6 cells | Rattus norvegicus | 25 | cell-based format | Scientific Literature | ||
| 10. | ALA1657785 | A | Permeability of the compound at pH 5 by PAMPA | 5 | assay format | Scientific Literature | |||
| 11. | ALA1657786 | A | Permeability of the compound at pH 6.5 by PAMPA | 5 | assay format | Scientific Literature | |||
| 12. | ALA2423111 | P | Aqueous solubility of the compound at pH 6.8 after 20 hrs by HPLC analysis | 5 | small-molecule physicochemical format | Scientific Literature | |||
| 13. | ALA2423114 | B | Selectivity ratio of IC50 for GlyT2 in Wistar rat brainstem cells to GlyT1 in rat C6 glioma cells | Rattus norvegicus | 29 | cell-based format | Scientific Literature | ||
| 14. | ALA2423115 | B | Displacement of [3H]glycine from GlyT2 in Wistar rat brainstem cells after 10 mins by scintillation counting analysis | Rattus norvegicus | 29 | cell-based format | Scientific Literature | ||
| 15. | ALA2423116 | B | Displacement of [3H]glycine from GlyT1 in rat C6 glioma cells incubated for 30 mins prior to substrate addition measured after 10 mins by scintillation counting analysis | Rattus norvegicus | 31 | cell-based format | Scientific Literature |
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