# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1654617 | Functional | Antiviral activity against ganciclovir-sensitive HCMV infected in HFF assessed as reduction in viral plaque formation after 8 days by microscopy | Human betaherpesvirus 5 | 3 | ALA1649293 | organism-based format | Scientific Literature | |
2. | ALA1654618 | Functional | Antiviral activity against ganciclovir-resistant HCMV infected in HFF assessed as reduction in viral plaque formation after 8 days by microscopy | Human betaherpesvirus 5 | 3 | ALA1649293 | organism-based format | Scientific Literature | |
3. | ALA1654619 | Functional | Antiviral activity against ganciclovir-sensitive HCMV infected in HFF assessed as cleavage of viral DNA concatemer at 30 uM measured after 72 hrs postinfection by PAGE | Human betaherpesvirus 5 | 1 | ALA1649293 | organism-based format | Scientific Literature | |
4. | ALA1654620 | Functional | Antiviral activity against ganciclovir-resistant HCMV infected in HFF assessed as cleavage of viral DNA concatemer at 30 uM measured after 72 hrs postinfection by PAGE | Human betaherpesvirus 5 | 1 | ALA1649293 | organism-based format | Scientific Literature | |
5. | ALA1654623 | Functional | Antiviral activity against ganciclovir-sensitive HCMV infected in HFF assessed as formation of viral capsid type A at 10 uM measured after 72 hrs postinfection by electron microscopy | Human betaherpesvirus 5 | 3 | ALA1649293 | organism-based format | Scientific Literature | |
6. | ALA1654624 | Functional | Antiviral activity against ganciclovir-sensitive HCMV infected in HFF assessed as formation of viral capsid type B at 10 uM measured after 72 hrs postinfection by electron microscopy | Human betaherpesvirus 5 | 3 | ALA1649293 | organism-based format | Scientific Literature | |
7. | ALA1654625 | Functional | Antiviral activity against ganciclovir-sensitive HCMV infected in HFF assessed as formation of viral capsid type C at 10 uM measured after 72 hrs postinfection by electron microscopy | Human betaherpesvirus 5 | 3 | ALA1649293 | organism-based format | Scientific Literature | |
8. | ALA1654626 | Functional | Antiviral activity against ganciclovir-resistant HCMV infected in HFF assessed as formation of viral capsid type A at 10 uM measured after 72 hrs postinfection by electron microscopy | Human betaherpesvirus 5 | 3 | ALA1649293 | organism-based format | Scientific Literature | |
9. | ALA1654627 | Functional | Antiviral activity against ganciclovir-resistant HCMV infected in HFF assessed as formation of viral capsid type B at 10 uM measured after 72 hrs postinfection by electron microscopy | Human betaherpesvirus 5 | 3 | ALA1649293 | organism-based format | Scientific Literature | |
10. | ALA1654745 | Functional | Antiviral activity against ganciclovir-resistant HCMV infected in HFF assessed as formation of viral capsid type C at 10 uM measured after 72 hrs postinfection by electron microscopy | Human betaherpesvirus 5 | 3 | ALA1649293 | organism-based format | Scientific Literature | |
11. | ALA1654746 | ADME | Cytotoxicity against HFF after 8 days by XTT assay | Homo sapiens | 3 | ALA1649293 | cell-based format | Scientific Literature | |
12. | ALA1654747 | ADME | Cytotoxicity against rat Rat2 cells after 8 days by XTT assay | Rattus norvegicus | 3 | ALA1649293 | cell-based format | Scientific Literature | |
13. | ALA1654748 | ADME | Cytotoxicity against mouse NIH/3T3 cells after 8 days by XTT assay | Mus musculus | 3 | ALA1649293 | cell-based format | Scientific Literature | |
14. | ALA1654749 | Functional | Antiviral activity against HCMV AD169 infected in HFF assessed as viral plaque formation at 5 uM after 8 days by microscopy relative to control | Human betaherpesvirus 5 | 3 | ALA1649293 | organism-based format | Scientific Literature | |
15. | ALA1654750 | Functional | Antiviral activity against Herpes simplex virus 1 KOS infected in HFF assessed as viral plaque formation at 5 uM after 8 days by microscopy relative to control | Human alphaherpesvirus 1 | 3 | ALA1649293 | organism-based format | Scientific Literature | |
16. | ALA1654751 | Functional | Antiviral activity against VZV OKA infected in HFF assessed as viral plaque formation at 5 uM after 8 days by microscopy relative to control | Human alphaherpesvirus 3 | 3 | ALA1649293 | organism-based format | Scientific Literature | |
17. | ALA1654752 | Functional | Antiviral activity against MCMV Smith infected in HFF assessed as viral plaque formation at 5 uM after 8 days by microscopy relative to control | Maize chlorotic mottle virus | 3 | ALA1649293 | organism-based format | Scientific Literature | |
18. | ALA1654753 | Functional | Antiviral activity against RCMV RA-70 infected in HFF assessed as viral plaque formation at 5 uM after 8 days by microscopy relative to control | Red clover mottle virus | 3 | ALA1649293 | assay format | Scientific Literature | |
19. | ALA1654754 | Unassigned | Selectivity index, ratio of CC50 for HFF to EC50 for ganciclovir-sensitive HCMV infected in HFF | 3 | ALA1649293 | assay format | Scientific Literature | ||
20. | ALA1654755 | Unassigned | Selectivity index, ratio of CC50 for HFF to EC50 for ganciclovir-resistant HCMV infected in HFF | 3 | ALA1649293 | assay format | Scientific Literature |