| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1659134 | A | Ratio of drug level in plasma to brain in Sprague-Dawley rat at 10 mg/kg, sc | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 2. | ALA1659135 | A | Drug level Sprague-Dawley rat brain at 10 mg/kg, sc after 1.5 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA1659136 | A | Drug level Sprague-Dawley rat brain at 10 mg/kg, sc after 0.5 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA1659137 | A | Drug level Sprague-Dawley rat cerebrospinal fluid at 10 mg/kg, sc after 1.5 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA1659138 | A | Drug level Sprague-Dawley rat cerebrospinal fluid at 10 mg/kg, sc after 0.5 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA1659139 | A | Drug level Sprague-Dawley rat spinal cord at 10 mg/kg, sc after 0.5 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA1659140 | A | Drug level Sprague-Dawley rat spinal cord at 10 mg/kg, sc after 1.5 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA1659141 | A | Drug level Sprague-Dawley rat plasma at 10 mg/kg, sc after 1.5 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA1659142 | A | Drug level Sprague-Dawley rat plasma at 10 mg/kg, sc after 0.5 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA1659143 | B | Selectivity ratio, ratio of Ki for human DOP receptor to Ki for human NOP receptor | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA1659144 | A | Half life in human liver microsomes at 1 uM by HPLC-MS/MS analysis | Homo sapiens | 3 | microsome format | Scientific Literature | ||
| 12. | ALA1659145 | B | Selectivity ratio, ratio of Ki for human KOP receptor to Ki for human NOP receptor | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA1659146 | B | Selectivity ratio, ratio of Ki for human MOP receptor to Ki for human NOP receptor | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA1659147 | F | Agonist activity at human KOP receptor expressed in HEK-293 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by liquid scintillation counting relative to enadoline | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 15. | ALA1659148 | F | Agonist activity at human KOP receptor expressed in HEK-293 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by liquid scintillation counting | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 16. | ALA1659149 | F | Agonist activity at human MOP receptor expressed in CHO-K1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by liquid scintillation counting relative to DAMGO | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 17. | ALA1659150 | F | Agonist activity at human MOP receptor expressed in CHO-K1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by liquid scintillation counting | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 18. | ALA1659151 | F | Agonist activity at human NOP receptor expressed in HEK293 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by liquid scintillation counting | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 19. | ALA1659152 | F | Agonist activity at human NOP receptor expressed in HEK293 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by liquid scintillation counting relative to N/OFQ | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 20. | ALA1659153 | B | Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 mins | Homo sapiens | 12 | cell-based format | Scientific Literature |
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