# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1656357 | F | Antinociceptive activity in icv dosed HSD:ICR(CD1) mouse by tail flick test | Mus musculus | 6 | ALA1649095 | organism-based format | Scientific Literature | |
2. | ALA1656358 | F | Antinociceptive activity in intrathecally dosed HSD:ICR(CD1) mouse by tail flick test | Mus musculus | 6 | ALA1649095 | organism-based format | Scientific Literature | |
3. | ALA1656359 | F | Potency index, ratio of antinociceptive ED50 in icv dosed HSD:ICR(CD1) mouse to antinociceptive ED50 in intrathecally dosed HSD:ICR(CD1) mouse | Mus musculus | 6 | ALA1649095 | organism-based format | Scientific Literature | |
4. | ALA1656360 | F | Ratio of antinociceptive ED80 in intrathecally dosed HSD:ICR(CD1) mouse coadministered with 2.5 nmol kappa opioid receptor antagonist norBNI to ED80 in intrathecally dosed HSD:ICR(CD1) mouse | Mus musculus | 1 | ALA1649095 | organism-based format | Scientific Literature | |
5. | ALA1656361 | F | Ratio of antinociceptive ED80 in intrathecally dosed HSD:ICR(CD1) mouse coadministered with 5 nmol delta opioid receptor antagonist NTI to ED80 in intrathecally dosed HSD:ICR(CD1) mouse | Mus musculus | 1 | ALA1649095 | organism-based format | Scientific Literature | |
6. | ALA1656362 | F | Ratio of antinociceptive ED80 in intrathecally dosed HSD:ICR(CD1) mouse coadministered with 6 pmol mu opioid receptor antagonist CTOP to ED80 in intrathecally dosed HSD:ICR(CD1) mouse | Mus musculus | 1 | ALA1649095 | organism-based format | Scientific Literature | |
7. | ALA1656363 | F | Agonist activity at kappa/delta opioid receptor expressed in HEK293 cells coexpressing chimeric Giiq protein assessed as stimulation of intracellular calcium | 1 | ALA1649095 | cell-based format | Scientific Literature | ||
8. | ALA1656364 | B | Selectivity for kappa/delta opioid receptor expressed in HEK293 cells over mu opioid receptor expressed in HEK293 cells by intracellular calcium release assay | 1 | ALA1649095 | cell-based format | Scientific Literature | ||
9. | ALA1656365 | B | Selectivity for kappa/delta opioid receptor expressed in HEK293 cells over kappa opioid receptor expressed in HEK293 cells by intracellular calcium release assay | 1 | ALA1649095 | cell-based format | Scientific Literature | ||
10. | ALA1656366 | B | Selectivity for kappa/delta opioid receptor expressed in HEK293 cells over kappa/mu opioid receptor expressed in HEK293 cells by intracellular calcium release assay | 1 | ALA1649095 | cell-based format | Scientific Literature | ||
11. | ALA1656367 | B | Selectivity for kappa/delta opioid receptor expressed in HEK293 cells over mu/delta opioid receptor expressed in HEK293 cells by intracellular calcium release assay | 1 | ALA1649095 | cell-based format | Scientific Literature |