# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1665862 | F | Antiviral activity against HBV infected in human HepG2(2.2.15) cells assessed as decrease in extracellular viral DNA level after 24 hrs by blot hybridization assay | Hepatitis B virus | 4 | ALA1649503 | organism-based format | Scientific Literature | |
2. | ALA1665863 | A | Cytotoxicity against human HepG2(2.2.15) cells after 24 hrs by neutral red assay | Homo sapiens | 4 | ALA1649503 | cell-based format | Scientific Literature | |
3. | ALA1665864 | U | Selectivity index, ratio of CC50 for human HepG2(2.2.15) cells to EC50 for HBV infected in human HepG2(2.2.15) cells | 4 | ALA1649503 | cell-based format | Scientific Literature | ||
4. | ALA1666217 | F | Antiviral activity against HBV infected in transgenic mouse assessed as decrease in liver viral DNA level at 4 mg/kg, po administered daily for 14 days measured post last dose | Hepatitis B virus | 4 | ALA1649503 | organism-based format | Scientific Literature | |
5. | ALA1776360 | A | Metabolic stability in human liver S9 fraction assessed as compound degradation at 10 uM after 90 mins by HPLC/MS/MS | Homo sapiens | 3 | ALA1772955 | subcellular format | Scientific Literature | |
6. | ALA1776361 | A | Metabolic stability in human liver S9 fraction assessed as compound degradation at 1 uM after 90 mins by HPLC/MS/MS | Homo sapiens | 3 | ALA1772955 | subcellular format | Scientific Literature | |
7. | ALA1776362 | A | Metabolic stability in human liver S9 fraction assessed as compound remaining at 1 uM after 90 mins by HPLC/MS/MS | Homo sapiens | 4 | ALA1772955 | subcellular format | Scientific Literature | |
8. | ALA1776363 | A | Metabolic stability in rhesus monkey liver S9 fraction assessed as compound remaining at 1 uM after 90 mins by HPLC/MS/MS | Macaca mulatta | 4 | ALA1772955 | subcellular format | Scientific Literature | |
9. | ALA1777571 | A | Metabolic stability in rhesus monkey liver S9 fraction assessed as compound disappearance at 1 uM after 45-70 mins by HPLC/MS/MS | Macaca mulatta | 3 | ALA1772955 | subcellular format | Scientific Literature | |
10. | ALA1777579 | T | Selectivity index, ratio of CC50 for human HFF cells to EC50 for Vaccinia virus Copenhagen | 11 | ALA1772955 | cell-based format | Scientific Literature | ||
11. | ALA1777580 | F | Antiviral activity against Vaccinia virus Copenhagen infected in human HFF cells after 3 days by plaque reduction assay | Vaccinia virus | 11 | ALA1772955 | organism-based format | Scientific Literature | |
12. | ALA1777581 | T | Selectivity index, ratio of CC50 for human HFF cells to EC50 for Cowpox virus (Brighton Red) | 11 | ALA1772955 | cell-based format | Scientific Literature | ||
13. | ALA1777582 | A | Cytotoxicity against human HFF cells assessed as reduction in cell viability after 7 days by neutral red uptake assay | Homo sapiens | 11 | ALA1772955 | cell-based format | Scientific Literature | |
14. | ALA1777583 | F | Antiviral activity against Cowpox virus (Brighton Red) infected in human HFF cells after 3 days by plaque reduction assay | Cowpox virus (Brighton Red) | 11 | ALA1772955 | cell-based format | Scientific Literature | |
15. | ALA1777584 | T | Selectivity index, ratio of CC50 for african green monkey BSC1 cells to EC50 for Ectromelia virus Moscow | 11 | ALA1772955 | cell-based format | Scientific Literature | ||
16. | ALA1777585 | A | Cytotoxicity against african green monkey BSC1 cells after 2 to 4 hrs by MTS assay | Chlorocebus aethiops | 11 | ALA1772955 | cell-based format | Scientific Literature | |
17. | ALA1777586 | F | Antiviral activity against Ectromelia virus Moscow infected in african green monkey BSC1 cells after 4 to 5 days by plaque reduction assay | Ectromelia virus Moscow | 11 | ALA1772955 | organism-based format | Scientific Literature |