# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA636947 | F | Evaluated for the inhibition of human gastrointestinal adenocarcinoma cells in vitro by HT-29 assay | Homo sapiens | 7 | ALA1123126 | cell-based format | Scientific Literature | |
2. | ALA636948 | F | Evaluated for the inhibition of human gastrointestinal adenocarcinoma cells in vitro by HuTu 80 assay | Homo sapiens | 7 | ALA1123126 | assay format | Scientific Literature | |
3. | ALA639911 | F | Evaluated for the inhibition of human gastrointestinal adenocarcinoma cells in vitro by SW480 assay | Homo sapiens | 7 | ALA1123126 | cell-based format | Scientific Literature | |
4. | ALA639912 | F | Evaluated for the inhibition of human gastrointestinal adenocarcinoma cells in vitro by WIDR assay | Homo sapiens | 7 | ALA1123126 | cell-based format | Scientific Literature | |
5. | ALA663133 | B | Binding energy to Streptococcus faecium dihydrofolate reductase | Enterococcus faecium | 68 | ALA1122106 | single protein format | Scientific Literature | |
6. | ALA663137 | B | Binding energy against Streptococcus faecium dihydrofolate reductase | Enterococcus faecium | 68 | ALA1121631 | single protein format | Scientific Literature | |
7. | ALA669446 | B | Inhibitory activity against dihydrofolate reductase (DHFR) obtained from human WIL2 cells | 25 | ALA1124218 | cell-based format | Scientific Literature | ||
8. | ALA666806 | B | Inhibitory activity against Leu22-Phe mutant human Dihydrofolate reductase | 16 | ALA1128249 | single protein format | Scientific Literature | ||
9. | ALA669640 | B | Evaluated for the inhibition of dihydrofolate reductase from L1210 mouse leukemia cells | 1 | ALA1123126 | cell-based format | Scientific Literature | ||
10. | ALA666696 | B | Inhibition of rat liver dihydrofolate reductase assayed spectrophotometrically at 340 nM | 5 | ALA1123126 | assay format | Scientific Literature | ||
11. | ALA700422 | F | Evaluated for 50% inhibition of growth of L1210 / R81 cells (48 h), relative to untreated controls | Mus musculus | 5 | ALA1123126 | cell-based format | Scientific Literature | |
12. | ALA700815 | F | Evaluated for the growth inhibition of L1210 /S cells | Mus musculus | 7 | ALA1123126 | cell-based format | Scientific Literature | |
13. | ALA701038 | F | Evaluated for the uptake of Methotrexate in L1210 leukemia cells | Mus musculus | 7 | ALA1123126 | cell-based format | Scientific Literature | |
14. | ALA815659 | B | Inhibitory activity against thymidylate synthase isolated from L1210 leukemia cells | 26 | ALA1124218 | cell-based format | Scientific Literature | ||
15. | ALA821382 | B | Inhibitory activity against Wild-type human DHFR | 6 | ALA1128249 | single protein format | Scientific Literature | ||
16. | ALA852242 | B | Selectivity ratio of Ki value against mutant DHFR and Wild-type DHFR | Homo sapiens | 6 | ALA1128249 | single protein format | Scientific Literature | |
17. | ALA3231104 | B | Inhibition of thymidylate synthetase in mouse L1210S cells | Mus musculus | 33 | ALA3227974 | cell-based format | Scientific Literature | |
18. | ALA3231105 | B | Inhibition of thymidylate synthetase in Lactobacillus casei | Lacticaseibacillus casei | 33 | ALA3227974 | single protein format | Scientific Literature | |
19. | ALA3231106 | B | Inhibition of dihydrofolate reductase in human acute lymphocytic leukemia cells | Homo sapiens | 48 | ALA3227974 | assay format | Scientific Literature | |
20. | ALA3280522 | B | Inhibition of Streptococcus faecium dihydrofolate reductase using dihydrofolate as substrate | Enterococcus faecium | 66 | ALA3272349 | single protein format | Scientific Literature |