# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1674453 | Functional | Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as inhibition of TNFalpha production at 1 to 15 uM after 18 hrs by ELISA | Mus musculus | 13 | ALA1671795 | cell-based format | Scientific Literature | |
2. | ALA1674454 | Functional | Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as inhibition of IL1-beta production at 1 to 15 uM after 18 hrs by ELISA | Mus musculus | 13 | ALA1671795 | cell-based format | Scientific Literature | |
3. | ALA1674455 | Functional | Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as inhibition of IL-6 production at 1 to 15 uM after 18 hrs by ELISA | Mus musculus | 13 | ALA1671795 | cell-based format | Scientific Literature | |
4. | ALA1674456 | Functional | Antiinflammatory activity against IFN-gamma-stimulated human HaCaT cells assessed as inhibition of chemokine MDC production at 50 to 100 uM after 18 hrs by ELISA | Homo sapiens | 80 | ALA1671795 | cell-based format | Scientific Literature | |
5. | ALA1674457 | ADME | Cytotoxicity against human HaCaT cells at 50 to 100 uM after 24 hrs by MTT assay | Homo sapiens | 80 | ALA1671795 | cell-based format | Scientific Literature | |
6. | ALA4236713 | Binding | Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ levels preincubated for 5 mins followed by agonist addition by Fuo-4-AM based spectrofluorimetry | Rattus norvegicus | 50 | ALA4229558 | cell-based format | Scientific Literature | |
7. | ALA4236714 | Binding | Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of CBD-induced Ca2+ levels preincubated for 5 mins followed by agonist addition by Fuo-4-AM based spectrofluorimetry | Rattus norvegicus | 50 | ALA4229558 | cell-based format | Scientific Literature | |
8. | ALA5227059 | Functional | Antiproliferative activity in human DMS-114 cells assessed as cell growth inhibition by MTT assay | Homo sapiens | 4 | ALA5226292 | cell-based format | Scientific Literature |