# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1674456 | F | Antiinflammatory activity against IFN-gamma-stimulated human HaCaT cells assessed as inhibition of chemokine MDC production at 50 to 100 uM after 18 hrs by ELISA | Homo sapiens | 80 | ALA1671795 | cell-based format | Scientific Literature | |
2. | ALA1674457 | A | Cytotoxicity against human HaCaT cells at 50 to 100 uM after 24 hrs by MTT assay | Homo sapiens | 80 | ALA1671795 | cell-based format | Scientific Literature | |
3. | ALA4236713 | B | Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ levels preincubated for 5 mins followed by agonist addition by Fuo-4-AM based spectrofluorimetry | Rattus norvegicus | 50 | ALA4229558 | cell-based format | Scientific Literature | |
4. | ALA4236714 | B | Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of CBD-induced Ca2+ levels preincubated for 5 mins followed by agonist addition by Fuo-4-AM based spectrofluorimetry | Rattus norvegicus | 50 | ALA4229558 | cell-based format | Scientific Literature | |
5. | ALA4236715 | B | Non-competitive antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ levels preincubated for 5 mins followed by agonist addition by Fuo-4-AM dependent spectrofluorimetry based Schild analysis | Rattus norvegicus | 3 | ALA4229558 | cell-based format | Scientific Literature | |
6. | ALA4416547 | F | Antiallergic activity in rat RBL2H3 cells assessed as inhibition of DNP-HSA-mediated degranulation by measuring decrease in beta-hexosaminidase activity preincubated for 30 mins followed by DNP-HSA stimulation and measured after 30 mins by 4-nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside substrate based assay | Rattus norvegicus | 63 | ALA4414618 | cell-based format | Scientific Literature |