# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1677384 | Functional | Antimicrobial activity against Trypanosoma cruzi Y infected in rat L6E9 myoblasts assessed as inhibition of [5,6-3H]uracil incorporation after 3 days postinfection by scintillation counter | Trypanosoma cruzi | 41 | ALA1671721 | organism-based format | Scientific Literature | |
2. | ALA1677385 | ADME | Cytotoxicity against rat L6E9 myoblasts at 1 to 25 uM | Rattus norvegicus | 50 | ALA1671721 | assay format | Scientific Literature | |
3. | ALA1677388 | Binding | Inhibition of Trypanosoma cruzi Y PDEC after 30 mins | Trypanosoma cruzi | 51 | ALA1671721 | single protein format | Scientific Literature | |
4. | ALA4483863 | Functional | Luciferase/luciferin-expressing antifolate-resistant parasites were used to infect a culture of HepG2 cells that were pre-incubated with compounds. Infected hepatocytes emit light due to the luciferase reaction. Assay results are presented as the percent inhibition of light emission compared to control. (Single Point Inhibition, %) | Plasmodium berghei | 9,989 | ALA4483862 | organism-based format | Winzeler Lab Plasmodium Screening Data | |
5. | ALA4483864 | Functional | Luciferase/luciferin-expressing antifolate-resistant parasites were used to infect a culture of HepG2 cells that were pre-incubated with compounds. Infected hepatocytes emit light due to the luciferase reaction. Assay results are presented as the percent inhibition of light emission compared to control. (Single Point Inhibition, %) | Homo sapiens | 9,989 | ALA4483862 | cell-based format | Winzeler Lab Plasmodium Screening Data |