| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1687466 | F | Vasodilatory activity in Sprague-Dawley rat thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction at 0.01 nM to 100 uM | Rattus norvegicus | 4 | ALA1681634 | tissue-based format | Scientific Literature | |
| 2. | ALA1687467 | F | Vasodilatory activity in Sprague-Dawley rat thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction compound treated 5 mins after 1 uM soluble guanylate cyclase inhibitor ODQ treatment | Rattus norvegicus | 4 | ALA1681634 | tissue-based format | Scientific Literature | |
| 3. | ALA1687468 | F | Vasodilatory activity in Sprague-Dawley rat thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction compound treated 5 mins after 200 uM NO-scavenger C-PTIO treatment | Rattus norvegicus | 4 | ALA1681634 | tissue-based format | Scientific Literature | |
| 4. | ALA1687469 | F | Vasodilatory activity in Sprague-Dawley rat thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction at 0.01 nM to 1 uM in presence of 21% oxygen | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
| 5. | ALA1687470 | F | Vasodilatory activity in Sprague-Dawley rat thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction at 0.01 nM to 1 uM in presence of 1% oxygen | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
| 6. | ALA1687471 | F | Vasodilatory activity in Sprague-Dawley rat thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction at 0.01 nM to 1 uM in presence 100 U/ml SOD at 21% oxygen | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
| 7. | ALA1687472 | F | Potentiation of Angeli's salt induced- vasodilatory activity in Sprague-Dawley rat thoracic aorta at 1 mM | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
| 8. | ALA1687473 | F | Potentiation of 1-Nitrosocyclohexyl trifluoroacetate induced- vasodilatory activity in Sprague-Dawley rat thoracic aorta at 1 mM | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
| 9. | ALA1687476 | F | Inhibition of Angeli's salt induced- vasodilatory activity in Sprague-Dawley rat thoracic aorta at 0.1 to 1 mM | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
| 10. | ALA1687477 | F | Inhibition of 1-Nitrosocyclohexyl trifluoroacetate induced- vasodilatory activity in Sprague-Dawley rat thoracic aorta at 0.1 to 1 mM | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
| 11. | ALA1687479 | F | Vasodilatory activity in rabbit thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction | Oryctolagus cuniculus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
| 12. | ALA1687480 | F | Vasodilatory activity in bovine intrapulmonary artery assessed as relaxation of phenylephrine-induced vasoconstriction | Bos taurus | 3 | ALA1681634 | assay format | Scientific Literature | |
| 13. | ALA1687481 | F | Ratio of compound EC50 to Angeli's salt EC50 for vasodilatory activity in rabbit thoracic aorta | Oryctolagus cuniculus | 1 | ALA1681634 | tissue-based format | Scientific Literature | |
| 14. | ALA1687482 | F | Ratio of compound EC50 to Angeli's salt EC50 for vasodilatory activity in bovine intrapulmonary artery | Bos taurus | 1 | ALA1681634 | assay format | Scientific Literature | |
| 15. | ALA2423753 | B | Inhibition of rabbit muscle GAPDH at 1 uM after 60 mins by spectrophotometry | Oryctolagus cuniculus | 3 | ALA2417429 | single protein format | Scientific Literature | |
| 16. | ALA2423754 | P | Half life of the compound in neutral buffer at 1 mM by stopped-flow UV-Vis spectrophotometry | 1 | ALA2417429 | small-molecule physicochemical format | Scientific Literature | ||
| 17. | ALA2423755 | P | Chemical stability of the compound in neutral buffer assessed as rate constant at 1 mM by stopped-flow UV-Vis spectrophotometry | 1 | ALA2417429 | small-molecule physicochemical format | Scientific Literature | ||
| 18. | ALA2423758 | B | Binding affinity to alkyl hydroperoxide reductase subunit C C165S mutant (unknown origin) assessed as formation of mixture of sulfinamide and sulfinic acid at Cys46 by LC-MS analysis | Not specified | 2 | ALA2417429 | assay format | Scientific Literature | |
| 19. | ALA2423761 | B | Binding affinity to alkyl hydroperoxide reductase subunit C C165S mutant (unknown origin) assessed as unreacted thiol in peptide D41 to G51 by LC-MS analysis | Not specified | 4 | ALA2417429 | assay format | Scientific Literature | |
| 20. | ALA2423962 | B | Binding affinity to alkyl hydroperoxide reductase subunit C C165S mutant peptide D41 to G51 (unknown origin) assessed as sulfinic acid or sulfinamide modification by MALDI-TOF MS | Not specified | 4 | ALA2417429 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!