# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1687466 | F | Vasodilatory activity in Sprague-Dawley rat thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction at 0.01 nM to 100 uM | Rattus norvegicus | 4 | ALA1681634 | tissue-based format | Scientific Literature | |
2. | ALA1687467 | F | Vasodilatory activity in Sprague-Dawley rat thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction compound treated 5 mins after 1 uM soluble guanylate cyclase inhibitor ODQ treatment | Rattus norvegicus | 4 | ALA1681634 | tissue-based format | Scientific Literature | |
3. | ALA1687468 | F | Vasodilatory activity in Sprague-Dawley rat thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction compound treated 5 mins after 200 uM NO-scavenger C-PTIO treatment | Rattus norvegicus | 4 | ALA1681634 | tissue-based format | Scientific Literature | |
4. | ALA1687469 | F | Vasodilatory activity in Sprague-Dawley rat thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction at 0.01 nM to 1 uM in presence of 21% oxygen | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
5. | ALA1687470 | F | Vasodilatory activity in Sprague-Dawley rat thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction at 0.01 nM to 1 uM in presence of 1% oxygen | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
6. | ALA1687471 | F | Vasodilatory activity in Sprague-Dawley rat thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction at 0.01 nM to 1 uM in presence 100 U/ml SOD at 21% oxygen | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
7. | ALA1687474 | F | Potentiation of 1-Nitrosocyclohexyl acetate induced- vasodilatory activity in Sprague-Dawley rat thoracic aorta at 1 mM | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
8. | ALA1687475 | F | Potentiation of MahmaNonoate induced- vasodilatory activity in Sprague-Dawley rat thoracic aorta at 1 mM | Rattus norvegicus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
9. | ALA1687478 | F | Inhibition of 1-Nitrosocyclohexyl acetate induced- vasodilatory activity in Sprague-Dawley rat thoracic aorta at 0.1 to 1 mM | Rattus norvegicus | 2 | ALA1681634 | tissue-based format | Scientific Literature | |
10. | ALA1687479 | F | Vasodilatory activity in rabbit thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction | Oryctolagus cuniculus | 3 | ALA1681634 | tissue-based format | Scientific Literature | |
11. | ALA1687480 | F | Vasodilatory activity in bovine intrapulmonary artery assessed as relaxation of phenylephrine-induced vasoconstriction | Bos taurus | 3 | ALA1681634 | assay format | Scientific Literature | |
12. | ALA2423753 | B | Inhibition of rabbit muscle GAPDH at 1 uM after 60 mins by spectrophotometry | Oryctolagus cuniculus | 3 | ALA2417429 | single protein format | Scientific Literature | |
13. | ALA2423759 | B | Binding affinity to alkyl hydroperoxide reductase subunit C C165S mutant (unknown origin) assessed as formation of sulfinic acid of Cys46 of peptide D41 to G51 by LC-MS analysis | Not specified | 2 | ALA2417429 | assay format | Scientific Literature | |
14. | ALA2423761 | B | Binding affinity to alkyl hydroperoxide reductase subunit C C165S mutant (unknown origin) assessed as unreacted thiol in peptide D41 to G51 by LC-MS analysis | Not specified | 4 | ALA2417429 | assay format | Scientific Literature | |
15. | ALA2423962 | B | Binding affinity to alkyl hydroperoxide reductase subunit C C165S mutant peptide D41 to G51 (unknown origin) assessed as sulfinic acid or sulfinamide modification by MALDI-TOF MS | Not specified | 4 | ALA2417429 | assay format | Scientific Literature | |
16. | ALA2423965 | B | Binding affinity to rabbit muscle GAPDH peptide V232 to R245 assessed as formation of sulfinic acid of Cys244 by LC-MS analysis | Oryctolagus cuniculus | 2 | ALA2417429 | single protein format | Scientific Literature | |
17. | ALA2423966 | B | Binding affinity to rabbit muscle GAPDH tryptic peptide I143 to K159 assessed as formation of disulfide bond by LC-MS analysis | Oryctolagus cuniculus | 6 | ALA2417429 | single protein format | Scientific Literature | |
18. | ALA2423968 | B | Binding affinity to rabbit muscle GAPDH assessed as structural modifications at 5 mM after 60 mins by SDS-PAGE | Oryctolagus cuniculus | 4 | ALA2417429 | single protein format | Scientific Literature | |
19. | ALA2423969 | B | Binding affinity to alkyl hydroperoxide reductase subunit C C165S mutant (unknown origin) assessed as structural modifications by SDS-PAGE | Not specified | 1 | ALA2417429 | assay format | Scientific Literature | |
20. | ALA2423970 | B | Reversible inhibition of rabbit muscle GAPDH assessed as residual enzyme activity at 1 uM after 60 mins followed by incubation with DTT by spectrophotometry relative to control | Oryctolagus cuniculus | 3 | ALA2417429 | single protein format | Scientific Literature |