# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1687099 | Binding | Inhibition of GATA4-DNA interaction in HEK293 nuclear extract at 50 uM after 15 mins by EMSA assay | Homo sapiens | 4 | ALA1681692 | cell-based format | Scientific Literature | |
2. | ALA1687100 | Binding | Inhibition of GATA4-DNA interaction in HEK293 nuclear extract at 100 uM after 15 mins by EMSA assay | Homo sapiens | 4 | ALA1681692 | cell-based format | Scientific Literature | |
3. | ALA1687102 | Binding | Inhibition of GATA4- mediated BNP promoter activation in HeLa cells at 100 uM after 24 hrs by luciferase reporter gene assay | Homo sapiens | 4 | ALA1681692 | cell-based format | Scientific Literature | |
4. | ALA1687103 | Binding | Inhibition of GATA4- DNA interaction in mouse C2C12 cells at 100 uM after 24 hrs by EMSA assay | Homo sapiens | 4 | ALA1681692 | cell-based format | Scientific Literature | |
5. | ALA1687104 | Binding | Inhibition of GATA4 in mouse C2C12 cells assessed as myoblast differentiation to myotubes at 100 uM after 48 hrs by immunofluorescence assay in presence of 0.5% FBS relative to control | Homo sapiens | 4 | ALA1681692 | cell-based format | Scientific Literature | |
6. | ALA1687105 | Binding | Inhibition of GATA4 in mouse C2C12 cells assessed as myoblast differentiation to myotubes at 100 uM after 48 hrs by immunofluorescence assay in presence of 20 % FBS relative to control | Homo sapiens | 4 | ALA1681692 | cell-based format | Scientific Literature | |
7. | ALA1687106 | Physicochemical | Lipophilicity, log P of compound | 4 | ALA1681692 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA1687107 | ADME | Drug uptake in human HeLa cells after 24 hrs | Homo sapiens | 4 | ALA1681692 | cell-based format | Scientific Literature | |
9. | ALA1687108 | Binding | Inhibition of GATA4-DNA interaction in HEK293 nuclear extract at 50 to 150 uM after 15 mins by EMSA assay | Homo sapiens | 4 | ALA1681692 | single protein format | Scientific Literature | |
10. | ALA1687109 | ADME | Cytotoxicity in human HeLa cells assessed as effect on cell proliferation upto 150 uM | Homo sapiens | 4 | ALA1681692 | cell-based format | Scientific Literature | |
11. | ALA1687110 | ADME | Cytotoxicity in human HEK293 cells assessed as effect on cell proliferation upto 150 uM | Homo sapiens | 4 | ALA1681692 | cell-based format | Scientific Literature | |
12. | ALA1687111 | ADME | Cytotoxicity in mouse C2C12 cells assessed as effect on cell proliferation upto 150 uM | Mus musculus | 4 | ALA1681692 | cell-based format | Scientific Literature | |
13. | ALA1687112 | ADME | Cytotoxicity in human HeLa cells assessed as cell death upto 150 uM | Homo sapiens | 4 | ALA1681692 | cell-based format | Scientific Literature | |
14. | ALA1687113 | ADME | Cytotoxicity in mouse C2C12 cells assessed as cell death upto 150 uM | Mus musculus | 4 | ALA1681692 | cell-based format | Scientific Literature | |
15. | ALA1687114 | ADME | Cytotoxicity in human HEK293 cells assessed as cell death upto 150 uM | Homo sapiens | 4 | ALA1681692 | cell-based format | Scientific Literature | |
16. | ALA1687115 | Binding | Effect on Tbx5 in HEK293 nuclear extract at 50 uM after 15 mins by EMSA assay | Homo sapiens | 4 | ALA1681692 | single protein format | Scientific Literature | |
17. | ALA1687116 | Binding | Effect on NFATc1 in HEK293 nuclear extract at 50 uM after 15 mins by EMSA assay | Homo sapiens | 4 | ALA1681692 | cell-based format | Scientific Literature | |
18. | ALA1963976 | Functional | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | 27,593 | ALA1201862 | cell-based format | PubChem BioAssays | ||
19. | ALA1963981 | Functional | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | 41,327 | ALA1201862 | cell-based format | PubChem BioAssays | ||
20. | ALA1963985 | Functional | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | 41,631 | ALA1201862 | cell-based format | PubChem BioAssays |