# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1686573 | B | Inhibition of Cathepsin V at 1 umol/L for 2 mins by spectrofluorometry | 6 | single protein format | Scientific Literature | |||
2. | ALA1686574 | B | Inhibition of Cathepsin S at 1 umol/L for 2 mins by spectrofluorometry | 6 | single protein format | Scientific Literature | |||
3. | ALA1686575 | B | Inhibition of Cathepsin V assessed as second-order inactivation rate constant by spectrofluorometry | 12 | single protein format | Scientific Literature | |||
4. | ALA1686576 | B | Inhibition of Cathepsin S assessed as second-order inactivation rate constant by spectrofluorometry | 12 | single protein format | Scientific Literature | |||
5. | ALA3117846 | P | Chemical stability of the compound under aqueous condition | 2 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA3117847 | A | Cytotoxicity against mouse NIH/3T3 cells assessed as cell viability at 10 to 100 umol/L after 2 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
7. | ALA3117848 | A | Cytotoxicity against mouse NIH/3T3 cells assessed as cell viability at 0.5 to 10 umol/L after 2 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
8. | ALA3117855 | B | Inhibition of trypsin like activity of beta2-20S proteasome in mouse NIH-3T3 cells at 2 times IC50 | Mus musculus | 4 | cell-based format | Scientific Literature | ||
9. | ALA3117856 | B | Inhibition of horse erythrocytes trypsin like activity of beta2-20S proteasome using z-ARR-AMC as substrate measured for 60 mins by fluorescence assay | Equus caballus | 12 | assay format | Scientific Literature | ||
10. | ALA3117857 | B | Inhibition of yeast 20S proteasome | Saccharomyces cerevisiae | 12 | assay format | Scientific Literature | ||
11. | ALA3117858 | B | Inhibition of horse erythrocytes trypsin like activity of beta2-20S proteasome using z-ARR-AMC as substrate at 100 uM measured for 60 mins by fluorescence assay | Equus caballus | 18 | assay format | Scientific Literature | ||
12. | ALA3117859 | B | Inhibition of horse erythrocytes chymotrypsin like activity of beta5-20S proteasome using suc-LLVY-AMC as substrate at 100 uM measured for 60 mins by fluorescence assay | Equus caballus | 12 | assay format | Scientific Literature | ||
13. | ALA3117860 | B | Inhibition of horse erythrocytes caspase like activity of beta1-20S proteasome using z-LLE-AMC as substrate at 100 uM measured for 60 mins by fluorescence assay | Equus caballus | 12 | assay format | Scientific Literature |