# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1686573 | B | Inhibition of Cathepsin V at 1 umol/L for 2 mins by spectrofluorometry | 6 | ALA1681765 | single protein format | Scientific Literature | ||
2. | ALA1686574 | B | Inhibition of Cathepsin S at 1 umol/L for 2 mins by spectrofluorometry | 6 | ALA1681765 | single protein format | Scientific Literature | ||
3. | ALA1686575 | B | Inhibition of Cathepsin V assessed as second-order inactivation rate constant by spectrofluorometry | 12 | ALA1681765 | single protein format | Scientific Literature | ||
4. | ALA1686576 | B | Inhibition of Cathepsin S assessed as second-order inactivation rate constant by spectrofluorometry | 12 | ALA1681765 | single protein format | Scientific Literature | ||
5. | ALA3117856 | B | Inhibition of horse erythrocytes trypsin like activity of beta2-20S proteasome using z-ARR-AMC as substrate measured for 60 mins by fluorescence assay | Equus caballus | 12 | ALA3112526 | assay format | Scientific Literature | |
6. | ALA3117857 | B | Inhibition of yeast 20S proteasome | Saccharomyces cerevisiae | 12 | ALA3112526 | assay format | Scientific Literature | |
7. | ALA3117858 | B | Inhibition of horse erythrocytes trypsin like activity of beta2-20S proteasome using z-ARR-AMC as substrate at 100 uM measured for 60 mins by fluorescence assay | Equus caballus | 18 | ALA3112526 | assay format | Scientific Literature | |
8. | ALA3117859 | B | Inhibition of horse erythrocytes chymotrypsin like activity of beta5-20S proteasome using suc-LLVY-AMC as substrate at 100 uM measured for 60 mins by fluorescence assay | Equus caballus | 12 | ALA3112526 | assay format | Scientific Literature | |
9. | ALA3117860 | B | Inhibition of horse erythrocytes caspase like activity of beta1-20S proteasome using z-LLE-AMC as substrate at 100 uM measured for 60 mins by fluorescence assay | Equus caballus | 12 | ALA3112526 | assay format | Scientific Literature | |
10. | ALA4341642 | F | Induction of morphological changes in human HT144 cells assessed as cell rounding at 10 uM incubated for 24 hrs by tubulin-Cy2 and TOPRO-3 staining based confocal microscopic method | Homo sapiens | 2 | ALA4340535 | cell-based format | Scientific Literature | |
11. | ALA4341643 | F | Induction of morphological changes in human HT144 cells assessed as membrane blebbing at 10 uM incubated for 24 hrs by tubulin-Cy2 and TOPRO-3 staining based confocal microscopic method | Homo sapiens | 2 | ALA4340535 | cell-based format | Scientific Literature | |
12. | ALA4341644 | B | Inhibition of human recombinant cathepsin B assessed as second-order inhibition rate constant using Z-RR-MCA as substrate incubated for 10 mins by spectrofluorimetric method | Homo sapiens | 2 | ALA4340535 | single protein format | Scientific Literature | |
13. | ALA4341645 | B | Inhibition of human recombinant cathepsin L expressed in Pichia pastoris assessed as second-order inhibition rate constant using Z-FR-MCA as substrate incubated for 10 mins by spectrofluorimetric method | Homo sapiens | 2 | ALA4340535 | assay format | Scientific Literature | |
14. | ALA4341646 | B | Inhibition of human recombinant cathepsin S assessed as second-order inhibition rate constant using Z-FR-MCA as substrate incubated for 10 mins by spectrofluorimetric method | Homo sapiens | 2 | ALA4340535 | single protein format | Scientific Literature | |
15. | ALA4341647 | F | Cytotoxicity against mouse B16F10Nex2 cells assessed as reduction in cell viability incubated for 16 hrs by MTT assay | Mus musculus | 2 | ALA4340535 | cell-based format | Scientific Literature | |
16. | ALA4341648 | A | Cytotoxicity against human HUVEC cells assessed as reduction in cell viability incubated for 16 hrs by MTT assay | Homo sapiens | 2 | ALA4340535 | cell-based format | Scientific Literature | |
17. | ALA4341649 | A | Cytotoxicity against mouse 3T3 cells assessed as reduction in cell viability incubated for 16 hrs by MTT assay | Mus musculus | 2 | ALA4340535 | cell-based format | Scientific Literature | |
18. | ALA4341650 | F | Cytotoxicity against human SK-MEL-25 cells assessed as reduction in cell viability incubated for 16 hrs by MTT assay | Homo sapiens | 2 | ALA4340535 | cell-based format | Scientific Literature | |
19. | ALA4341651 | F | Cytotoxicity against human SK-MEL-28 cells assessed as reduction in cell viability incubated for 16 hrs by MTT assay | Homo sapiens | 2 | ALA4340535 | cell-based format | Scientific Literature | |
20. | ALA4341652 | F | Cytotoxicity against human A2058 cells assessed as reduction in cell viability incubated for 16 hrs by MTT assay | Homo sapiens | 2 | ALA4340535 | cell-based format | Scientific Literature |