| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1686964 | B | Displacement of [3H]AVP from human V1b receptor expressed in CHO cells co-expressing VIP-luciferase by whole cell binding assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
| 2. | ALA1686965 | A | Metabolic stability of the compound in human liver microsomes assessed as compound remaining after 30 mins | Homo sapiens | 12 | microsome format | Scientific Literature | ||
| 3. | ALA1686967 | B | Displacement of [3H]AVP from human vasopressin V1b receptor expressed in CHO cells by whole cell binding assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA1686968 | B | Displacement of [3H]AVP from rat vasopressin V1b receptor expressed in CHO cells by whole cell binding assay | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA1686969 | B | Displacement of [3H]AVP from human vasopressin V1a receptor at 5 uM | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 6. | ALA1686970 | B | Displacement of [3H]AVP from human vasopressin V2 receptor | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 7. | ALA1686971 | B | Displacement of [3H]oxytocin from human oxytocin receptor | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 8. | ALA1686972 | A | Clearance in Wistar rat at 2 mg/kg, iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 9. | ALA1686973 | A | Elimination half life in Wistar rat at 2 mg/kg, iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 10. | ALA1686974 | A | Volume of distribution at steady state in Wistar rat at 2 mg/kg, iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 11. | ALA1686975 | A | AUC in Wistar rat at 2 mg/kg, iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 12. | ALA1686976 | A | AUC in Wistar rat at 5 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 13. | ALA1686977 | A | Oral bioavailability in Wistar rat at 2 mg/kg | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 14. | ALA1686978 | A | Inhibition of human cytochrome P450 | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA1686979 | F | Reduction in dDAVP/CRH-induced ACTH release in po dosed rat plasma in rat HPA hyperactivity model compound pretreated 2 hrs before dDAVP/CRH challenge by ELISA | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA1686980 | F | Reduction in dDAVP/CRH-induced ACTH release in rat plasma in rat HPA hyperactivity model at 5 mg/kg, po pretreated 2 hrs before dDAVP/CRH challenge by ELISA | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA1686981 | A | Cmax in human at 25 mg/kg, po | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA1686982 | A | AUC in human at 25 mg/kg, po | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA1686983 | A | Tmax in human at 25 mg/kg, po | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA1686984 | A | Half life in human at 25 mg/kg, po | Homo sapiens | 1 | organism-based format | Scientific Literature |
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