| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1687309 | F | Antiproliferative activity against mouse NIH/3T3 cells assessed as suppression of cell viability at 50 uM after 24 hrs by CyQuant cell viability assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA1687310 | F | Antiproliferative activity against human HL60 cells assessed as suppression of cell viability after 24 hrs by CyQuant cell viability assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA1687311 | B | Inhibition of STAT3 dimerization in v-Src transformed mouse NIH3T3 cells assessed as suppression of STAT3-DNA binding activity in nucleus at 100 uM after 24 hrs by electrophoretic mobility shift assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA1687312 | B | Inhibition of STAT3 dimerization in v-Src transformed mouse NIH3T3 cells assessed as suppression of STAT3-DNA binding activity in nucleus at 100 uM after 6 hrs by electrophoretic mobility shift assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA1687313 | B | Displacement of 5-carboxyfluorescein-GpYDKPHVL-NH2 from mouse recombinant His-tagged STAT1-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assay | Mus musculus | 2 | assay format | Scientific Literature | ||
| 6. | ALA1687314 | B | Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assay | Mus musculus | 12 | assay format | Scientific Literature | ||
| 7. | ALA1687315 | B | Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 mins by electrophoretic mobility shift assay | Mus musculus | 14 | cell-based format | Scientific Literature | ||
| 8. | ALA1687317 | A | Apparent permeability across apical to basolateral side in human Caco2 cells at 10 uM at pH 7.4 after 90 mins by LC/MS analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA1687318 | B | Inhibition of mouse recombinant SH2 domain of His-tagged full-length STAT3 by surface plasmon resonance assay | Mus musculus | 5 | single protein format | Scientific Literature | ||
| 10. | ALA1687319 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as suppression of cell viability at 50 uM after 24 hrs by CyQuant cell viability assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA1687320 | F | Antiproliferative activity against human PANC1 cells assessed as suppression of cell viability at 50 uM after 24 hrs by CyQuant cell viability assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA1687465 | F | Antiproliferative activity against human DU145 cells assessed as suppression of cell viability at 50 uM after 24 hrs by CyQuant cell viability assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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