# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1687390 | Binding | Displacement of biotinylated phosphatidylinositol-3,4,5-phosphate from mouse AKT1 PH domain by surface plasmon resonance competitive binding assay | Mus musculus | 49 | ALA1681784 | single protein format | Scientific Literature | |
2. | ALA1687391 | Functional | Cytotoxicity against human BxPC3 cells by MTT assay | Homo sapiens | 49 | ALA1681784 | cell-based format | Scientific Literature | |
3. | ALA3888333 | Binding | SPR Competitive Binding Assay: SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biacore) as described in Mol Cancer Ther 7:2621 (2008). For the competitive binding assays and the Ki determination, PtdIns(3,4,5)phosphate-biotin labeled liposomes (Echelon Biosciences) and SA chips were used with increasing concentrations of the compound tested. | 32 | ALA3886664 | single protein format | BindingDB Database |