| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1697031 | B | Inhibition of Clostridium botulinum BoNT/A-mediated neuromuscular block in CD1 mouse phrenic nerve hemidiaphragm assessed as time required to 50% loss of twitch tension at 10 uM after 15 to 20 mins | Clostridium botulinum | 2 | ALA1687736 | single protein format | Scientific Literature | |
| 2. | ALA1697033 | B | Inhibition of zinc carboxypeptidase A at up to 20 uM | 5 | ALA1687736 | assay format | Scientific Literature | ||
| 3. | ALA1697034 | B | Inhibition of Clostridium botulinum BoNT/A light chain-mediated SNAP-25 cleavage in mouse Neuro2a cells at 10 uM after 30 mins by Western blotting | Clostridium botulinum | 5 | ALA1687736 | cell-based format | Scientific Literature | |
| 4. | ALA1697035 | B | Inhibition of Clostridium botulinum BoNT/A light chain-mediated SNAP-25 cleavage in mouse Neuro2a cells at 15 uM after 30 mins by Western blotting | Clostridium botulinum | 5 | ALA1687736 | cell-based format | Scientific Literature | |
| 5. | ALA1697036 | B | Inhibition of protease activity of recombinant full-length Clostridium botulinum BoNT/A light chain at 200 uM after 5 mins by HPLC-based assay | Clostridium botulinum | 12 | ALA1687736 | single protein format | Scientific Literature | |
| 6. | ALA1697038 | B | Inhibition of protease activity of recombinant full-length Clostridium botulinum BoNT/B light chain at 20 uM after 5 mins by HPLC-based assay | Clostridium botulinum | 5 | ALA1687736 | single protein format | Scientific Literature | |
| 7. | ALA1697040 | B | Inhibition of protease activity of recombinant full-length Clostridium botulinum BoNT/A light chain after 5 mins by HPLC-based assay | Clostridium botulinum | 5 | ALA1687736 | single protein format | Scientific Literature | |
| 8. | ALA1697041 | B | Inhibition of protease activity of recombinant Clostridium botulinum BoNT/A (1 to 425) light chain after 5 mins by HPLC-based assay | Clostridium botulinum | 5 | ALA1687736 | single protein format | Scientific Literature | |
| 9. | ALA1697042 | B | Inhibition of protease activity of recombinant Clostridium botulinum BoNT/E light chain expressed in Escherichia coli (pET24a+/BL21(DE3)) assessed as cleavage of SNAP-25 at 240 uM after 30 mins by SDS-PAGE analysis | Clostridium botulinum | 5 | ALA1687736 | assay format | Scientific Literature | |
| 10. | ALA1794424 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] | 30,565 | ALA1201862 | assay format | PubChem BioAssays | ||
| 11. | ALA1794553 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] | Homo sapiens | 58,172 | ALA1201862 | cell-based format | PubChem BioAssays | |
| 12. | ALA1963976 | F | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | 27,593 | ALA1201862 | cell-based format | PubChem BioAssays | ||
| 13. | ALA1963981 | F | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | 41,327 | ALA1201862 | cell-based format | PubChem BioAssays | ||
| 14. | ALA1963985 | F | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | 41,631 | ALA1201862 | cell-based format | PubChem BioAssays | ||
| 15. | ALA1963989 | F | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | 41,040 | ALA1201862 | cell-based format | PubChem BioAssays | ||
| 16. | ALA1963990 | F | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | 40,970 | ALA1201862 | cell-based format | PubChem BioAssays | ||
| 17. | ALA1963991 | F | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | 36,454 | ALA1201862 | cell-based format | PubChem BioAssays | ||
| 18. | ALA1963994 | F | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | 37,749 | ALA1201862 | cell-based format | PubChem BioAssays | ||
| 19. | ALA1964017 | F | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | 28,020 | ALA1201862 | cell-based format | PubChem BioAssays | ||
| 20. | ALA1964018 | F | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | 38,940 | ALA1201862 | cell-based format | PubChem BioAssays |
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