# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1693607 | F | Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of CCL2-induced chemotaxis | Homo sapiens | 14 | ALA1687928 | cell-based format | Scientific Literature | |
2. | ALA1693608 | P | Aqueous solubility of the compound at pH 1.2 | 2 | ALA1687928 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA1693609 | P | Aqueous solubility of the compound at pH 7.4 | 2 | ALA1687928 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA1693610 | A | Cytotoxicity against human THP1 cells | Homo sapiens | 2 | ALA1687928 | cell-based format | Scientific Literature | |
5. | ALA1693611 | F | Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of CCL2-induced chemotaxis after 2 hrs trans-well migration assay | Homo sapiens | 2 | ALA1687928 | cell-based format | Scientific Literature | |
6. | ALA1693612 | F | Antagonist activity at CCR2 in human PBMC cells assessed as inhibition of CCL2-induced chemotaxis after 2 hrs trans-well migration assay | Homo sapiens | 2 | ALA1687928 | cell-based format | Scientific Literature | |
7. | ALA1693891 | F | Antagonist activity at CCR1 in human PBMC cells assessed as inhibition of CCL3-induced chemotaxis after 2 hrs trans-well migration assay | Homo sapiens | 2 | ALA1687928 | cell-based format | Scientific Literature | |
8. | ALA1693892 | F | Antagonist activity at CCR5 in human PBMC cells assessed as inhibition of CCL3-induced chemotaxis after 2 hrs trans-well migration assay | Homo sapiens | 2 | ALA1687928 | cell-based format | Scientific Literature | |
9. | ALA1693893 | F | Antagonist activity at CCR5 in human PBMC cells assessed as inhibition of CCL4-induced chemotaxis after 2 hrs trans-well migration assay | Homo sapiens | 2 | ALA1687928 | cell-based format | Scientific Literature | |
10. | ALA1693894 | F | Antagonist activity at CCR1 in human PBMC cells assessed as inhibition of CCL5-induced chemotaxis after 2 hrs trans-well migration assay | Homo sapiens | 2 | ALA1687928 | cell-based format | Scientific Literature | |
11. | ALA1693895 | F | Antagonist activity at CCR3 in human PBMC cells assessed as inhibition of CCL5-induced chemotaxis after 2 hrs trans-well migration assay | Homo sapiens | 2 | ALA1687928 | cell-based format | Scientific Literature | |
12. | ALA1693896 | F | Antagonist activity at CCR5 in human PBMC cells assessed as inhibition of CCL5-induced chemotaxis after 2 hrs trans-well migration assay | Homo sapiens | 2 | ALA1687928 | cell-based format | Scientific Literature | |
13. | ALA1693897 | F | Antagonist activity at CCR1 in eosinophil cells assessed as inhibition of CCL11-induced chemotaxis after 2 hrs trans-well migration assay | 2 | ALA1687928 | cell-based format | Scientific Literature | ||
14. | ALA1693898 | F | Antagonist activity at CCR3 in eosinophil cells assessed as inhibition of CCL11-induced chemotaxis after 2 hrs trans-well migration assay | 2 | ALA1687928 | cell-based format | Scientific Literature | ||
15. | ALA1693899 | F | Antagonist activity at CCR4 in transfected in THP-1 cells assessed as inhibition of CCL17-induced chemotaxis after 2 hrs trans-well migration assay | 2 | ALA1687928 | cell-based format | Scientific Literature | ||
16. | ALA1693900 | F | Antagonist activity at CXCR1 in human PMN cells assessed as inhibition of CXCL8-induced chemotaxis after 2 hrs trans-well migration assay | Homo sapiens | 2 | ALA1687928 | cell-based format | Scientific Literature | |
17. | ALA1693901 | F | Antagonist activity at CXCR2 in human PMN cells assessed as inhibition of CXCL8-induced chemotaxis after 2 hrs trans-well migration assay | Homo sapiens | 2 | ALA1687928 | cell-based format | Scientific Literature | |
18. | ALA1693902 | B | Displacement of [125I]CCL2 from CCR2 in human THP-1 cells | Homo sapiens | 2 | ALA1687928 | cell-based format | Scientific Literature | |
19. | ALA1693903 | B | Displacement of [125I]CCL2 from CCR2 in human HEK293 cells | Homo sapiens | 2 | ALA1687928 | cell-based format | Scientific Literature | |
20. | ALA1693904 | B | Displacement of [125I]CCL17 from CCR4 in human CHO-K1 cells | Homo sapiens | 1 | ALA1687928 | cell-based format | Scientific Literature |