| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3541530 | ADME | Drug metabolism in human liver microsomes assessed as UGT-mediated glucuronidation per mg of protein after 10 to 30 mins by HPLC analysis in presence of UDP-GlcUA | Homo sapiens | 3 | ALA3525932 | assay format | Scientific Literature | |
| 2. | ALA3541531 | ADME | Drug metabolism in human liver cytosol assessed as COMT-mediated methylation after 10 to 30 mins by HPLC analysis in presence of SAM | Homo sapiens | 3 | ALA3525932 | assay format | Scientific Literature | |
| 3. | ALA3541532 | ADME | Drug metabolism in human liver microsomes assessed as CYP450-mediated catecholization per mg of protein after 10 to 30 mins by HPLC analysis in presence of NADPH | Homo sapiens | 5 | ALA3525932 | assay format | Scientific Literature | |
| 4. | ALA3541533 | ADME | Drug metabolism in human liver cytosol assessed as COMT-mediated methylation per mg of protein after 10 to 30 mins by HPLC analysis in presence of SAM | Homo sapiens | 3 | ALA3525932 | assay format | Scientific Literature | |
| 5. | ALA3541534 | ADME | Drug metabolism in Sprague-Dawley rat liver microsomes assessed as CYP450-mediated catecholization after 10 to 30 mins by HPLC analysis in presence of NADPH | Rattus norvegicus | 5 | ALA3525932 | assay format | Scientific Literature | |
| 6. | ALA3541535 | ADME | Drug metabolism in Sprague-Dawley rat liver microsomes assessed as CYP450-mediated catecholization per mg of protein after 10 to 30 mins by HPLC analysis in presence of NADPH | Rattus norvegicus | 4 | ALA3525932 | assay format | Scientific Literature | |
| 7. | ALA3541810 | ADME | Drug metabolism in Sprague-Dawley rat liver microsomes assessed as UGT-mediated glucuronidation per mg of protein after 10 to 30 mins by HPLC analysis in presence of UDP-GlcUA | Rattus norvegicus | 3 | ALA3525932 | assay format | Scientific Literature | |
| 8. | ALA3541811 | ADME | Drug metabolism in Sprague-Dawley rat liver microsomes assessed as UGT-mediated glucuronidation after 10 to 30 mins by HPLC analysis in presence of UDP-GlcUA | Rattus norvegicus | 3 | ALA3525932 | assay format | Scientific Literature | |
| 9. | ALA3539361 | ADME | Drug metabolism in Sprague-Dawley rat liver cytosol assessed as COMT-mediated methylation after 10 to 30 mins by HPLC analysis in presence of SAM | Rattus norvegicus | 3 | ALA3525932 | assay format | Scientific Literature | |
| 10. | ALA3539362 | ADME | Drug metabolism in Sprague-Dawley rat liver cytosol assessed as COMT-mediated methylation per mg of protein after 10 to 30 mins by HPLC analysis in presence of SAM | Rattus norvegicus | 3 | ALA3525932 | assay format | Scientific Literature | |
| 11. | ALA3539363 | ADME | Activity of recombinant human CYP2C19 expressed in Saccharomyces cerevisiae AH22 cells assessed as enzyme-mediated sesamin dicatechol formation after 15 mins by HPLC analysis in presence of NADPH | Homo sapiens | 1 | ALA3525932 | cell-based format | Scientific Literature | |
| 12. | ALA3539666 | ADME | Activity of recombinant human CYP2C9 expressed in Saccharomyces cerevisiae AH22 cells assessed as enzyme-mediated sesamin dicatechol formation after 15 mins by HPLC analysis in presence of NADPH | Homo sapiens | 1 | ALA3525932 | cell-based format | Scientific Literature | |
| 13. | ALA3540150 | ADME | Activity of recombinant human CYP2C19 expressed in Saccharomyces cerevisiae AH22 cells assessed as enzyme-mediated compound formation treated with sesamin at 2 to 20 uM after 15 mins by HPLC analysis in presence of NADPH | Homo sapiens | 2 | ALA3525932 | cell-based format | Scientific Literature | |
| 14. | ALA3540470 | ADME | Drug metabolism in human liver microsomes assessed as CYP450-mediated catecholization after 10 to 30 mins by HPLC analysis in presence of NADPH | Homo sapiens | 5 | ALA3525932 | assay format | Scientific Literature | |
| 15. | ALA3540471 | ADME | Drug metabolism in human liver microsomes assessed as UGT-mediated glucuronidation after 10 to 30 mins by HPLC analysis in presence of UDP-GlcUA | Homo sapiens | 3 | ALA3525932 | assay format | Scientific Literature | |
| 16. | ALA3537642 | ADME | Drug level in human liver microsomes treated with sesamin after 30 mins by HPLC analysis in presence of NADPH | Homo sapiens | 1 | ALA3525932 | assay format | Scientific Literature | |
| 17. | ALA1694357 | Functional | Activation of Nrf2/ARE in rat PC12 cells assessed as upregulation of HO-1 protein expression at 10 uM after 12 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA1687931 | cell-based format | Scientific Literature | |
| 18. | ALA1694358 | Functional | Induction of nuclear translocation of Nrf2 in rat PC12 cells at 10 uM after 6 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA1687931 | cell-based format | Scientific Literature | |
| 19. | ALA1694359 | Functional | Activation of Nrf2/ARE in rat PC12 cells assessed as upregulation of HO-1 protein expression at 10 uM after 6 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA1687931 | cell-based format | Scientific Literature | |
| 20. | ALA1694360 | Functional | Activation of Nrf2/ARE in rat PC12 cells assessed as upregulation of HO-1 mRNA expression at 10 uM after 6 hrs by RT-PCR | Rattus norvegicus | 1 | ALA1687931 | cell-based format | Scientific Literature |
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