# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA630197 | P | Partition coefficient in octanol-buffer at a pH 7.4 | 8 | ALA1124010 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA633535 | P | Ionization constant in presence of nitrogen | 8 | ALA1124010 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA634057 | P | Ionization constant in presence of hydroxyl | 8 | ALA1124010 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA663103 | B | Potency to displace the specific in vitro binding of [3H]N-0437 to calf striatal membrane | Bos taurus | 7 | ALA1124010 | assay format | Scientific Literature | |
5. | ALA667481 | B | Affinity for [3H]N-propylnorapomorphine (NPA) Dopamine receptor D2 | 3 | ALA1124965 | single protein format | Scientific Literature | ||
6. | ALA675835 | B | In vitro affinity to dopamine receptor using [3H]HPD as radioligand in rat striatal membranes | 3 | ALA1124290 | cell membrane format | Scientific Literature | ||
7. | ALA675836 | B | In vitro affinity to dopamine receptor using [3H]NPAD as radioligand in rat striatal membranes | 3 | ALA1124290 | cell membrane format | Scientific Literature | ||
8. | ALA671399 | B | Concentration inhibiting specific binding of [3H]haloperidol to Dopamine receptor D2 from rat striatal brain. | 4 | ALA1124965 | assay format | Scientific Literature | ||
9. | ALA735247 | F | Inhibition of locomotor activity (LMA) in mice by the compound administered intraperitoneally. | Mus musculus | 4 | ALA1124965 | organism-based format | Scientific Literature | |
10. | ALA735249 | F | Inhibition of locomotor activity (LMA) in mice generated from four doses of 5-12 animals per dose (dose administered subcutaneously) | Mus musculus | 3 | ALA1124965 | organism-based format | Scientific Literature | |
11. | ALA770866 | B | Potency to displace the specific in vitro binding of [3H]DP-5,6-ADTN to rat striatal membrane | 7 | ALA1124010 | assay format | Scientific Literature | ||
12. | ALA775832 | F | Inhibition of dopamine neuronal firing activity in the rat substantia nigra DA neutrons (2.2 mg/kg administered intraperitoneally) | Rattus norvegicus | 3 | ALA1124965 | organism-based format | Scientific Literature | |
13. | ALA780201 | F | Reversal of reserpine-induced depression in rat (dose administered subcutaneously) Values generated from three doses;5-10 rats were used per dose. | Rattus norvegicus | 1 | ALA1124965 | organism-based format | Scientific Literature | |
14. | ALA780781 | F | Dose (ip) giving half-maximal reversal of the gamma-butyrolactone-induced increase in DOPA formation of rat striatum | Rattus norvegicus | 3 | ALA1124290 | organism-based format | Scientific Literature | |
15. | ALA776430 | F | Dose required for inhibition of locomotor activity in mice (sc) | Rattus norvegicus | 3 | ALA1124290 | organism-based format | Scientific Literature | |
16. | ALA776433 | F | Dose required for reversal of reserpine-induced depression in mice (sc) | Rattus norvegicus | 3 | ALA1124290 | organism-based format | Scientific Literature | |
17. | ALA782271 | F | Inhibition of gamma-butyrolactone-stimulated DOPA synthesis in the corpus striatum of rats (dose administered subcutaneously) | Rattus norvegicus | 3 | ALA1124965 | organism-based format | Scientific Literature | |
18. | ALA787604 | F | Inhibition of gamma-butyrolactone-stimulated DOPA synthesis in the corpus striatum of rats (30 mg/kg administered intraperitoneally) | Rattus norvegicus | 3 | ALA1124965 | organism-based format | Scientific Literature | |
19. | ALA851313 | F | Ratio of ED50 values for the inhibition of locomotor activity to reversal of reserpine-induced depression | 3 | ALA1124290 | assay format | Scientific Literature |