# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA664430 | B | Inhibition of dihydrofolate reductase from Pneumocystis carinii. | 17 | ALA1128273 | single protein format | Scientific Literature | ||
2. | ALA666660 | B | Inhibitory activity against isolated chicken liver dihydrofolate reductase (DHFR) | Gallus gallus | 75 | ALA1122558 | assay format | Scientific Literature | |
3. | ALA664886 | B | Inhibition of Escherichia coli dihydrofolate reductase. | 32 | ALA1122876 | single protein format | Scientific Literature | ||
4. | ALA859309 | B | Inhibitory activity against DHFR isolated from murine L5178Y tumor cells resistant to methotrexate | 1 | ALA1122587 | cell-based format | Scientific Literature | ||
5. | ALA669625 | B | Inhibitory activity against DHFR isolated from murine L5178Y tumor cells sensitive to methotrexate | 1 | ALA1122587 | cell-based format | Scientific Literature | ||
6. | ALA667186 | B | Inhibition constant against binding of Escherichia coli dihydrofolate reductase | Escherichia coli | 72 | ALA1124156 | single protein format | Scientific Literature | |
7. | ALA667809 | B | Binding affinity for dihydrofolate reductase from Lactobacillus casei | Lacticaseibacillus casei | 47 | ALA1130169 | single protein format | Scientific Literature | |
8. | ALA857514 | B | Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR) | Lacticaseibacillus casei | 44 | ALA1121755 | single protein format | Scientific Literature | |
9. | ALA668388 | B | Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR) | Lacticaseibacillus casei | 75 | ALA1122558 | single protein format | Scientific Literature | |
10. | ALA875027 | B | Inhibition of dihydrofolate reductase (DHFR) from Leishmania major | Leishmania major | 46 | ALA1123784 | single protein format | Scientific Literature | |
11. | ALA666237 | B | Inhibition of dihydrofolate reductase | 36 | ALA1122259 | single protein format | Scientific Literature | ||
12. | ALA858233 | F | Inhibition of growth of methotrexate resistant (MB1428) strain of Escherichia coli cells | Escherichia coli | 16 | ALA1122876 | organism-based format | Scientific Literature | |
13. | ALA681594 | F | Inhibition of growth of methotrexate sensitive (MB1417) strain of Escherichia coli cells | Escherichia coli | 16 | ALA1122876 | organism-based format | Scientific Literature | |
14. | ALA704963 | F | Inhibitory activity against methotrexate- resistant Lactobacillus casei cells | Lacticaseibacillus casei | 32 | ALA1121755 | organism-based format | Scientific Literature | |
15. | ALA704964 | F | Inhibitory activity against methotrexate- sensitive Lactobacillus casei cells | Lacticaseibacillus casei | 41 | ALA1121755 | organism-based format | Scientific Literature | |
16. | ALA858248 | F | Concentration required for inhibition of murine leukemia L5178Y cells | Mus musculus | 42 | ALA1122006 | cell-based format | Scientific Literature | |
17. | ALA707335 | F | Compound was tested in vitro for concentration required to decrease 50% growth rate of murine leukemia L5178Y/R cell culture | Mus musculus | 46 | ALA1122007 | cell-based format | Scientific Literature | |
18. | ALA3635309 | B | Binding affinity to Escherichia coli DHFR assessed as change in melting temperature at 500 uM using spyro orange reporter dye by differential scanning fluorimetry | Escherichia coli | 14 | ALA3632554 | single protein format | Scientific Literature | |
19. | ALA3635311 | B | Binding affinity to Escherichia coli DHFR at 500 uM using spyro orange reporter dye by differential scanning fluorimetry | Escherichia coli | 14 | ALA3632554 | single protein format | Scientific Literature | |
20. | ALA3635313 | B | Inhibition of Escherichia coli DHFR assessed as NADP formation | Escherichia coli | 16 | ALA3632554 | single protein format | Scientific Literature |