# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1738018 | F | PUBCHEM_BIOASSAY: Confirmation Concentration-Response Assay for Enhancers of SMN2 Splice Variant Expression for Further Probe SAR. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1474] | Homo sapiens | 109 | ALA1201862 | assay format | PubChem BioAssays | |
2. | ALA1737944 | F | PUBCHEM_BIOASSAY: Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Modulation of SMN1 Expression for Further Probe SAR. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1474] | Homo sapiens | 61 | ALA1201862 | assay format | PubChem BioAssays | |
3. | ALA1738105 | F | PUBCHEM_BIOASSAY: Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Interaction with Luciferase Reporter for Further Probe SAR. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1474] | Photinus pyralis | 94 | ALA1201862 | assay format | PubChem BioAssays | |
4. | ALA1826374 | A | Apparent permeability from basolateral side to apical side of human Caco2 cells at 10 uM | Homo sapiens | 10 | ALA1821687 | cell-based format | Scientific Literature | |
5. | ALA1826375 | A | Apparent permeability from apical side to basolateral side of human Caco2 cells at 10 uM | Homo sapiens | 10 | ALA1821687 | cell-based format | Scientific Literature | |
6. | ALA1826376 | A | Half-life in mouse liver microsome at 1 uM | Mus musculus | 10 | ALA1821687 | microsome format | Scientific Literature | |
7. | ALA1826377 | B | Inhibition of fire fly luciferase | Luciola lateralis | 10 | ALA1821687 | single protein format | Scientific Literature | |
8. | ALA1826378 | B | Activation of SMN in human fibroblast cells obtained from type 1 SMA patients assessed as protein punctuate bodies per 100 nuclei at 37 to 3000 nM | Homo sapiens | 1 | ALA1821687 | cell-based format | Scientific Literature | |
9. | ALA1826380 | B | Activation of SMN expressed in HEK293 cells assessed as rate of induction by SMN2-promotor driven luciferase reporter gene assay relative to basal level | 98 | ALA1821687 | cell-based format | Scientific Literature | ||
10. | ALA1826381 | B | Activation of SMN expressed in HEK293 cells assessed as concentration required to reach 50% of maximum luciferase signal by SMN2-promotor driven luciferase reporter gene assay | 133 | ALA1821687 | cell-based format | Scientific Literature |