# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA640155 | P | Partition coefficient (logP) | 82 | ALA1122169 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA644757 | A | Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats. | Rattus norvegicus | 82 | ALA1122169 | microsome format | Scientific Literature | |
3. | ALA687550 | B | Inhibitory activity against murine gelatinase B at 5 mM was determined | 14 | ALA1134870 | single protein format | Scientific Literature | ||
4. | ALA879772 | B | Inhibition of gelatinase B, matrix metalloprotease-9 (MMP-9) at 5000 uM | 1 | ALA1148343 | single protein format | Scientific Literature | ||
5. | ALA3053541 | B | Antagonist activity at 5-HT2B in Rattus norvegicus CD (rat) stomach fundus sections assessed as inhibition of serotonin-induced contractile response at 10 '-5 M after 1 hr | Rattus norvegicus | 6 | ALA3045258 | single protein format | Scientific Literature | |
6. | ALA3053542 | B | Non-surmountable antagonist activity at 5-HT2B in Rattus norvegicus CD (rat) stomach fundus sections assessed as inhibition of serotonin-induced contractile response after 1 hr | Rattus norvegicus | 21 | ALA3045258 | single protein format | Scientific Literature | |
7. | ALA3053543 | B | Displacement of [3H]mesulergine from 5-HT2C in Rattus norvegicus CD (rat) stomach fundus sections at 10 uM after 1 hr | Rattus norvegicus | 21 | ALA3045258 | single protein format | Scientific Literature | |
8. | ALA3053544 | B | Displacement of [3H]ketansarin from 5-HT2A in Rattus norvegicus CD (rat) stomach fundus sections at 10 uM after 1 hr | Rattus norvegicus | 21 | ALA3045258 | single protein format | Scientific Literature | |
9. | ALA3053546 | B | Binding affinity to 5-HT2B in Rattus norvegicus CD (rat) stomach fundus sections after 1 hr | Rattus norvegicus | 23 | ALA3045258 | single protein format | Scientific Literature | |
10. | ALA3301363 | P | ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake flask method described in J. Biomol. Screen. 2011, 16, 348-355. Experimental range -1.5 to 4.5 | 4,197 | ALA3301361 | small-molecule physicochemical format | AstraZeneca Deposited Data | ||
11. | ALA4477150 | B | Inhibition of human LOXL2 expressed in CHO cells incubated for 2 hrs followed by 1,5-Diaminopentane addition by Amplex Red fluorescence based assay | Homo sapiens | 93 | ALA4476887 | cell-based format | Patent Bioactivity Data | |
12. | ALA5149905 | B | Inhibition of recombinant human QC using H-Gln-AMC hydrobromide as fluorogenic substrate incubated for 6 hrs by fluorometric microplate reader analysis | Homo sapiens | 69 | ALA5143758 | single protein format | Scientific Literature |