PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125]
PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory)
Agonist activity at human RARalpha expressed in HEK293 cells assessed as transcriptional activation at 1 to 100 uM after 40 hrs by luciferase reporter gene assay
Agonist activity at human RARalpha expressed in HEK293 cells assessed as transcriptional activation at 1 to 100 uM after 40 hrs by luciferase reporter gene assay in presence of RAR antagonist LE135
Agonist activity at human RXRalpha expressed in HEK293 cells assessed as transcriptional activation up to 100 uM after 40 hrs by luciferase reporter gene assay
Agonist activity at human RARalpha expressed in HEK293 cells assessed as transcriptional activation at 0.1 to 50 uM after 40 hrs by luciferase reporter gene assay
Agonist activity at PPARgamma (unknown origin) expressed in HEK293 cells assessed as transcriptional activation at 1 to 25 uM after 40 hrs by luciferase reporter gene assay
Agonist activity at PPARdelta (unknown origin) expressed in HEK293 cells assessed as transcriptional activation at 1 to 25 uM after 40 hrs by luciferase reporter gene assay
Agonist activity at LXR-alpha (unknown origin) expressed in HEK293 cells assessed as transcriptional activation at 1 to 25 uM after 40 hrs by luciferase reporter gene assay