# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1819659 | Binding | Inhibition of human TS assessed as oxidation of tetrahydrofolate to dihydrofolate after 2 to 12 mins by spectrophotometry | Homo sapiens | 9 | ALA1817595 | single protein format | Scientific Literature | |
2. | ALA1819660 | Binding | Inhibition of Escherichia coli TS assessed as oxidation of tetrahydrofolate to dihydrofolate after 2 to 12 mins by spectrophotometry | Escherichia coli | 9 | ALA1817595 | single protein format | Scientific Literature | |
3. | ALA1819661 | Binding | Inhibition of Toxoplasma gondii TS assessed as oxidation of tetrahydrofolate to dihydrofolate after 2 to 12 mins by spectrophotometry | Toxoplasma gondii | 9 | ALA1817595 | single protein format | Scientific Literature | |
4. | ALA1819662 | Binding | Inhibition of human DHFR by spectrophotometry | Homo sapiens | 9 | ALA1817595 | single protein format | Scientific Literature | |
5. | ALA1819663 | Binding | Inhibition of Escherichia coli DHFR by spectrophotometry | Escherichia coli | 9 | ALA1817595 | single protein format | Scientific Literature | |
6. | ALA1819664 | Binding | Inhibition of Toxoplasma gondii DHFR by spectrophotometry | Toxoplasma gondii | 9 | ALA1817595 | single protein format | Scientific Literature | |
7. | ALA1819666 | Binding | Ratio of premetrexed IC50 to compound IC50 for human TS | Homo sapiens | 4 | ALA1817595 | single protein format | Scientific Literature | |
8. | ALA1819668 | Binding | Selectivity index, ratio of IC50 for Escherichia coli DHFR to IC50 for human DHFR | 2 | ALA1817595 | assay format | Scientific Literature |